Results 121 to 130 of about 236,715 (297)

Etherification of Bio‐Based Furanic Compounds via Continuous Flow

open access: yesAdvanced Sustainable Systems, EarlyView.
A comprehensive investigation on the etherification of bio‐based furanic compounds using a continuous flow apparatus. Reaction conditions are optimized for the synthesis of BEMF and then used to obtain a library of BAMFs. Additionally, the self‐etherification of HMF to produce OBMF is explored both in heterogeneous and by employing the homogeneous ...
Davide Dalla Torre   +4 more
wiley   +1 more source

Automated Transcranial Photobiomodulation in Healthy Rats: Effects on Working Memory and Brain Markers

open access: yesAdvanced Therapeutics, EarlyView.
Transcranial photobiomodulation (PBM) enhances spatial working memory in healthy rats under both continuous and alternating stimulation protocols. At the neural level, PBM modulates cytochrome c oxidase activity, increases prefrontal and hippocampal synaptic markers, and induces region‐specific c‐Fos expression. These effects suggest improved cognitive
Candela Zorzo   +6 more
wiley   +1 more source

Limitations of Hyperbaric Oxygenation in Occlusive Arterial Disease [PDF]

open access: bronze, 1965
James F. Gorman   +2 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

open access: yesAdvanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi   +5 more
wiley   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

open access: yesAdvanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo   +10 more
wiley   +1 more source

Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation

open access: yesAdvanced Science, EarlyView.
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo   +4 more
wiley   +1 more source

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