Results 151 to 160 of about 347,511 (234)

Establishment of rat model for aspiration pneumonia and potential mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Aspiration pneumonia was induced in Sprague Dawley rats by intratracheal instillation of hydrochloric acid (HCl, 1.5 μL/g.wt, pH = 1) followed by lipopolysaccharide (LPS, 20 μg/g.wt) after 1 h. The model reproduced hallmark features of acute lung injury, including histological lung damage, microvascular dysfunction, inflammation, hypoxemia, and ...
Hanbing Hu   +7 more
wiley   +1 more source

α‐Amination of 1,3‐Dicarbonyl Compounds and Analogous Reactive Enolate‐Precursors Using Ammonia under Oxidative Conditions

open access: yesAngewandte Chemie, EarlyView.
Using ammonia in combination with hypochlorites as simple oxidants under phase‐transfer conditions allows for the direct oxidative α‐amination of reactive enolate precursors such as cyclic β‐ketoesters, oxindoles, as well as malonitriles and malonates with good to excellent yields.
Christopher Mairhofer   +6 more
wiley   +2 more sources

An optimized perfusate for enhanced rat ex vivo lung perfusion and lung transplant models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We explored a low‐cost and efficient perfusate composition for use in rat ex vivo lung perfusion (EVLP) and lung transplant models. This perfusate demonstrates better biocompatibility, likely due to a reduction in immune responses associated with high doses of xenogenic proteins, resulting in less lung injury posttransplantation.
Jie Zhang, Xuanlin Zhang, Jianxing He
wiley   +1 more source

Spatiotemporal Super‐Resolution Imaging of Lipid Metabolism Dynamics in Physiological/Pathological Conditions

open access: yesAngewandte Chemie, EarlyView.
A novel polarity‐sensitive fluorescent probe was developed for the selective targeting of lipid droplets, enabling precise visualization and quantification of lipid metabolism disorders using an integrated STED‐FLIM platform. This probe allows accurate monitoring of lipid metabolism in cellular and pathological contexts, such as atherosclerosis ...
Shixian Cao   +7 more
wiley   +2 more sources

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou   +3 more
wiley   +1 more source

In Situ Observation of Post‐CO Intermediates to Decode C─C Coupling Pathways in CO2 Electroreduction

open access: yesAngewandte Chemie, EarlyView.
Resonance Raman spectroscopy (RRS) was used to observe the in situ CO2 electroreduction process by designing copper electrodes with unique structures. This dynamic observation allowed for the capture of the C─C coupling process, where CH2 asymmetrically couples with CO to form CH2CO.
Mingxu Sun   +9 more
wiley   +2 more sources

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