Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Clinical impact of treprostinil in neonates with persistent pulmonary hypertension refractory to inhaled nitric oxide: A retrospective cohort study. [PDF]
Medicine (Baltimore)Kim TH, Youn SE, Chung SH.
europepmc +1 more source
Real-time assessment of graft oxygenation and perfusion using spectral imaging for improved outcome in esophageal cancer surgery [PDF]
Jens De Winne +6 more
openalex +1 more source
Successful Use of Extracorporeal Membrane Oxygenation Postpartum as Rescue Therapy in a Woman With COVID-19 [PDF]
, 2020 Antonio Fiore +6 more
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Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Advanced Science, EarlyView.Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Reversible Changes in the NEM-reactive--SH Groups of Hemoglobin on Oxygenation-deoxygenation [PDF]
, 1962 Ayers, Valborg E. +3 more
core +3 more sources
Descriptor-Driven Prediction of Adsorption Energy of Oxygenates on Metal Dioxide Surfaces [PDF]
Chen Chen +4 more
openalex +1 more source
Advanced Science, EarlyView.Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source