Results 121 to 130 of about 11,177 (296)

The Effect of High Nitric Oxide Concentrations on Oxygenators in Cardiopulmonary Bypass Machines (Experimental Study)

open access: yesОбщая реаниматология
The aim of the study. To study the effect of high nitric oxide concentrations on hollow polypropylene fibers of oxygenators.Materials and methods. The study was conducted in two stages.
A. M. Radovskiy   +17 more
doaj   +1 more source

Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride

open access: yesAdvanced Science, EarlyView.
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee   +10 more
wiley   +1 more source

A drive mechanism for a blood pump integrated in an oxygenator

open access: yesCurrent Directions in Biomedical Engineering, 2018
The achievement of a low priming volume of the components in an extracorporeal perfusion system for neonatal and pediatric patients is an open research question.
Aghababaei Amin   +2 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

open access: yesAdvanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha   +5 more
wiley   +1 more source

The proposed use of performance indices to evaluate and compare the Gish Vision membrane oxygenator. [PDF]

open access: yes, 1998
The objective of this investigation was to evaluate and compare the recently released Gish Vision oxygenator with previously studied oxygenators. We utilized our previously described membrane oxygenator evaluation techniques as well as proposed the use ...
Mattioni, G J   +4 more
core  

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

To oxygenate or not to oxygenate – that is the question!

open access: yesInternational Wound Journal, 2007
Douglas, Queen, Keith G, Harding
openaire   +3 more sources

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun   +7 more
wiley   +1 more source

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