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Oxygenator impact on meropenem/vaborbactam in extracorporeal membrane oxygenation circuits

Perfusion, 2021
Introduction: To determine the oxygenator impact on alterations of meropenem (MEM)/vaborbactam (VBR) in a contemporary neonatal/pediatric (1/4-inch) and adolescent/adult (3/8-inch) extra corporeal membrane oxygenation (ECMO) circuit including the Quadrox-
Jeffrey J. Cies   +8 more
semanticscholar   +1 more source

Oxygenator impact on voriconazole in extracorporeal membrane oxygenation circuits

Perfusion, 2020
Introduction: To determine the oxygenator impact on alterations of voriconazole in a contemporary neonatal/pediatric (1/4 inch) and adolescent/adult (3/8 inch) extracorporeal membrane oxygenation circuit including the Quadrox-i® oxygenator.
Jeffrey J. Cies   +7 more
semanticscholar   +1 more source

Extracorporeal membrane oxygenation and V/Q ratios: an ex vivo analysis of CO2 clearance within the Maquet Quadrox-iD oxygenator

Perfusion, 2020
While hypercapnia is typically well treated with modern membrane oxygenators, there are cases where respiratory acidosis persists despite maximal extracorporeal membrane oxygenation support.
B. Zakhary, J. Sheldrake, V. Pellegrino
semanticscholar   +1 more source

Computed tomography angiography as an adjunct to computational fluid dynamics for prediction of oxygenator thrombus formation

Perfusion, 2020
Introduction: Extracorporeal membrane oxygenation circuit performance can be compromised by oxygenator thrombosis. Stagnant blood flow in the oxygenator can increase the risk of thrombus formation.
R. G. Conway   +6 more
semanticscholar   +1 more source

Oxygenator Impact on Ceftolozane and Tazobactam in Extracorporeal Membrane Oxygenation Circuits

Pediatric Critical Care Medicine, 2020
Objectives: To determine the oxygenator impact on alterations of ceftolozane/tazobactam in a contemporary neonatal/pediatric (1/4-inch) and adolescent/adult (3/8-inch) extracorporeal membrane oxygenation circuit including the Quadrox-i oxygenator (Maquet,
Jeffrey J. Cies   +5 more
semanticscholar   +1 more source

Oxygen transport— the oxygen delivery controversy

Intensive Care Medicine, 2004
Most cellular activities require energy in the form of oxygen, primarily obtained from the degradation of adenosine triphosphate (ATP) and other high-energy compounds. Oxygen must be present in sufficient amounts in the mitochondria to maintain effective concentrations of ATP in the electron transport system.
Vincent, Jean Louis, De Backer, Daniel
openaire   +3 more sources

Oxygen therapy and oxygen toxicity

Annals of Emergency Medicine, 1983
When oxygen therapy is warranted, the minimum effective dose generally should be given. Hypoxemic patients who have normal baseline ABG may be treated initially with an intermediate to high FiO2 in the range of 35% to 100%, depending on the severity of the respiratory distress. The majority of patients with exacerbations of COPD who are not in extremis
Peter Tinits, Peter Tinits
openaire   +3 more sources

Propofol-based sedation does not negatively influence oxygenator running time compared to midazolam in patients with extracorporeal membrane oxygenation

International Journal of Artificial Organs, 2019
Objective: Patients on extracorporeal membrane oxygenation are frequently in need for sedation. Use of propofol has been associated with impaired oxygenator function due to adsorption to the membrane as well as lipid load.
W. Lamm   +11 more
semanticscholar   +1 more source

Technical Indicators to Evaluate the Degree of Large Clot Formation Inside the Membrane Fiber Bundle of an Oxygenator in an In Vitro Setup

Artificial Organs, 2018
The most common technical complication during ECMO is clot formation. A large clot inside a membrane oxygenator reduces effective membrane surface area and therefore gas transfer capabilities, and restricts blood flow through the device, resulting in an ...
A. Kaesler   +8 more
semanticscholar   +1 more source

The Oxygen Therapy

Current Medicinal Chemistry, 2013
Oxygen (O(2)) is a vital element. Shortage of O(2) results in deranged metabolism and important changes in vascular tone with opposite effects on the systemic and pulmonary circulation. During hypoxemia, oxidative stress exposes the organism to a sort of accelerated senescence as well as to several acute untoward effects.
Corsonello, A.   +5 more
openaire   +3 more sources

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