Results 21 to 30 of about 9,818 (189)

The oxyhemoglobin reaction of nitric oxide [PDF]

Proceedings of the National Academy of Sciences, 1999
The oxidation of nitric oxide (NO) to nitrate by oxyhemoglobin is a fundamental reaction that shapes our understanding of NO biology. This reaction is considered to be the major pathway for NO elimination from the body; it is the basis for a prevalent NO assay; it is a critical feature in the modeling of NO diffusion in the circulatory ...
A J, Gow, B P, Luchsinger, J R, Pawloski, D J, Singel, J S, Stamler   +4 more
openaire   +2 more sources

Influence of Obstructive Sleep Apnea on Maternal and Perinatal Outcomes in Patients With Gestational Diabetes Mellitus

Journal of Sleep Research, EarlyView.
ABSTRACT The prevalence of obstructive sleep apnea (OSA) increases during pregnancy and is associated with gestational diabetes mellitus (GDM), although its clinical impact on birth outcomes remains unclear. We aimed to assess the effect of several OSA criteria and intermittent hypoxia in the third trimester on perinatal outcomes in women with GDM.
María Cerdà Moncadas, Oleksandr Serednytskyy, Ainhoa Álvarez Ruiz De Larrinaga, Laura Cànaves‐Gómez, Andrés Sánchez Barón, Mercedes Codina Marcet, Mónica De La Peña Bravo, Amanda Iglesias Coma, Daniel Morell‐Garcia, José Antonio Peña Zarza, María Paloma Giménez Carrero, María Concepción Piñas Cebrian, Susana García Fernández, Francisco García‐Río, Alberto Alonso‐Fernández   +14 more
wiley   +1 more source

Thermal-induced force release in oxyhemoglobin [PDF]

Scientific Reports, 2015
AbstractOxygen is released to living tissues via conformational changes of hemoglobin from R-state (oxyhemoglobin) to T-state (desoxyhemoglobin). The detailed mechanism of this process is not yet fully understood. We have carried out micromechanical experiments on oxyhemoglobin crystals to determine the behavior of the Young’s modulus and the internal ...
S. G. Gevorkian, A. E. Allahverdyan, D. S. Gevorgyan, Chin-Kun Hu   +3 more
openaire   +2 more sources

Locomotor muscle dysfunction and rehabilitative exercise training in fibrotic interstitial lung disease: Where are we at and where could we go?

Experimental Physiology, EarlyView.
Abstract Exercise limitation is a cardinal feature of fibrotic interstitial lung disease arising from pulmonary gas exchange, respiratory mechanical and cardio‐circulatory abnormalities. More recently, it has been recognized that impairment in locomotor muscle function (e.g., reduced muscle mass/strength or heightened fatigability) might also play a ...
Sarah Thivent, J. Alberto Neder, Anne‐Catherine Bernard, Marie Coudurier, Michel Guinot, Frédéric Hérengt, Samuel Verges, Mathieu Marillier   +7 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

The acute effect of two exercise modalities on neurocognitive responses in postmenopausal women: A randomized controlled trial

Experimental Physiology, EarlyView.
Abstract Menopause‐related cognitive decline, often worsened by vasomotor symptoms (VMS), might be mitigated by high cardiorespiratory fitness (CRF). Although acute exercise supports neurocognitive function, its effects vary by exercise and individual characteristics.
Morgane Le Bourvellec, Nathalie Delpech, Laurent Bosquet, Geoffroy Boucard, Carina Enea   +4 more
wiley   +1 more source

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

Experimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster, Travis Dylan Gibbons, Hannah Grace Caldwell, Connor A. Howe, Jennifer S. Duffy, Andrew R. Steele, Justin A. Monteleone, Jay M. J. R. Carr, Jodie Lauren Koep, Tenasia D. R. Monaghan, David B. MacLeod, Philip N. Ainslie   +11 more
wiley   +1 more source

Assembly of human adult and sickle hemoglobins from their oxygenated subunits. Differential rates of beta chain tetramer dissociation.

Journal of Biological Chemistry, 1981
The rate of assembly of oxyhemoglobins A and S at pH 7 and 20 degrees C has been followed spectrophotometrically at 582.5 nm, a maximum of the difference spectrum of isolated oxygenated subunits and intact oxyhemoglobin.
M. Mcdonald
semanticscholar   +1 more source

Effectiveness of convalescent plasma therapy in severe COVID-19 patients

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance COVID-19 is currently a big threat to global health. However, no specific antiviral agents are available for its treatment. In this work, we explore the feasibility of convalescent plasma (CP) transfusion to rescue severe patients.
Kai Duan, Bende Liu, Cesheng Li, Huajun Zhang, Ting Yu, J. Qu, Min Zhou, Li Chen, S. Meng, Yong Hu, Cheng Peng, Mingchao Yuan, Jinyan Huang, Zejun Wang, Jianhong Yu, Xiaoxiao Gao, Dan-qing Wang, Xiaoqi Yu, Li Li, Jiayou Zhang, Xiao Wu, Bei Li, Yanping Xu, Wei Chen, Yan Peng, Yeqin Hu, Lianzhen Lin, Xuefei Liu, Shihe Huang, Zhijun Zhou, Lianghao Zhang, Yue Wang, Zhi Zhang, K. Deng, Zhiwu Xia, Q. Gong, Wei Zhang, Xiaobei Zheng, Y. Liu, Huichuan Yang, Dongbo Zhou, Ding Yu, J. Hou, Zhènglì Shí, Saijuan Chen, Zhu Chen, Xinxin Zhang, Xiaoming Yang   +47 more
semanticscholar   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source