Results 31 to 40 of about 1,164 (177)

A Multimodal Machine Learning Model for Framingham Risk Score–Based Cardiovascular Risk Stratification in Patients With Obstructive Sleep Apnea

Journal of Sleep Research, EarlyView.
ABSTRACT Machine learning provides a powerful tool to capture complex, nonlinear patterns in biomedical data and enhance precision risk stratification. In this study, we applied a multilayer perceptron (MLP) framework to classify Framingham Risk Score–based cardiovascular risk categories in patients with obstructive sleep apnea (OSA).
Feng Zhao, Yin Li, Chenyang Li, Huajun Xu, Enhui Zhou, Weijun Huang, Huaming Zhu, Jian Guan, Hongliang Yi, Jianyin Zou, Nutan Chen   +10 more
wiley   +1 more source

Does Hypoxic Burden Better Explain Sex Differences in Functional Impairments Than Apnoea‐Hypopnoea Index in Obstructive Sleep Apnoea?

Journal of Sleep Research, EarlyView.
ABSTRACT Women with obstructive sleep apnoea (OSA) report more severe functional impairments than men, despite lower apnoea‐hypopnoea index (AHI) values. This raises questions about the adequacy of AHI for capturing OSA severity. We explored sex differences in functional outcomes in OSA patients and examined whether AHI or hypoxic burden (HB) better ...
Urvashi Nanda, Yu Sun Bin, Philip de Chazal, Andrew S. L. Chan, Amanda Piper, Kristina Kairaitis, Peter A. Cistulli, Brendon J. Yee, on behalf of the Sydney Sleep Biobank Investigators, Peter Cistulli, Philip de Chazal, Yu Sun Bin, Lu Fu, Benjamin Tong, Glenn Stewart, Gary Cohen, Andrew S. L. Chan, Anna Mohammadieh, John Wheatley, Kristina Kairaitis, Stephen Lambert, Tracey Burns, Brendon Yee, Amanda Piper, Kerri Melehan, Amy Jackson, Gislaine Gauthier   +26 more
wiley   +1 more source

Impact of Hypoxemia Severity on Cardiac Autonomic Regulation in Children With Sleep‐Disordered Breathing: A McGill Oximetry‐Based Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep‐related breathing disorders (SRBD) represent a significant paediatric health concern. Traditional polysomnographic indices, such as the apnoea–hypopnoea index, may not fully capture the physiological burden of paediatric SRBD, highlighting the need to better characterise the impact of nocturnal hypoxemia on cardiac autonomic regulation ...
Gintare Oboleviciene, Ausra Snipaitiene, Valdone Miseviciene   +2 more
wiley   +1 more source

Resynchronisation of the Biological Clock Using Exposure to Low Oxygen Levels in Humans: An Exploratory Study

Journal of Sleep Research, EarlyView.
ABSTRACT Exposure to reduced oxygen levels occurs in several real‐world contexts, such as during air travel or altitude exposure, and emerging evidence suggests that hypoxia may interact with molecular pathways involved in circadian regulation. This exploratory study investigated the effects of normobaric hypoxia on circadian phase shifting in humans ...
Renée Morin, Geneviève Forest, Kim Isabelle‐Nolet, Vincent Bourgon, Félix‐Gabriel Duval, Jean‐François Mauger, Pascal Imbeault   +6 more
wiley   +1 more source

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

Experimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster, Travis Dylan Gibbons, Hannah Grace Caldwell, Connor A. Howe, Jennifer S. Duffy, Andrew R. Steele, Justin A. Monteleone, Jay M. J. R. Carr, Jodie Lauren Koep, Tenasia D. R. Monaghan, David B. MacLeod, Philip N. Ainslie   +11 more
wiley   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise

Experimental Physiology, EarlyView.
Abstract A lack of consensus remains on whether normobaric hypoxia (NH) and hypobaric hypoxia (HH) may differentially impact physiological factors affecting cerebrovascular regulation, particularly with an additional strenuous exercise component. We sought to compare the acute effects of NH and HH on global cerebral blood flow (gCBF) at an altitude ...
Rachel Turner, Giovanni Vinetti, Giacomo Strapazzon, Hannes Gatterer   +3 more
wiley   +1 more source

Filter Design to Eliminate Motion Artifact of Pulse Oximetery

, 2001
Oxygen saturation of blood is defined as ratio of total hemoglobins density to oxyhemoglobins density And the accuracy of pulse oxymeter that measures the oxygen saturation of blood by a noninvasive method is influenced by a measuring environment ...
김남현
core  

Sex differences in the prefrontal cortex and muscle oxygenation during exercise until exhaustion in endurance‐trained individuals

Experimental Physiology, EarlyView.
Abstract figure legend During cardiopulmonary exercise testing, the decline in oxygenation in the prefrontal cortex of women is striking. This crucial brain area is directly involved in planning motor tasks. The decline is particularly pronounced at higher exercise intensities, especially after reaching the respiratory compensation point or anaerobic ...
Daniel Ramos‐López, Raúl Caulier‐Cisterna, Benjamín Díaz‐Ortiz, Cristóbal Baumann‐Biancani, Kamilo Hunger‐Abbott, Matías Herrera‐Matas, Andrés Vega‐Moraga, Vitor A. Lira, Maximiliano Espinosa‐Ramírez, Karol Ramírez‐Parada, Luigi Gabrielli‐Nervi, Hugo E. Verdejo, Felipe Contreras‐Briceño   +12 more
wiley   +1 more source

Vascular and skeletal muscle oxidative capacity responses to continuous double and single leg cycling

Experimental Physiology, EarlyView.
Abstract The purpose of this work was to determine endothelial, microvascular, skeletal muscle oxidative capacity (SMOC) and cardiorespiratory responses to an acute bout of continuous single leg cycling (SLC) and double leg cycling (DLC). Ten recreationally active men and women volunteered to participate in this investigation and reported to the ...
Edward Z. Pelka, B. Ryan Davis, John McDaniel   +2 more
wiley   +1 more source