Results 51 to 60 of about 11,883 (171)

Lateral Mucosal Flap With Steroid‐Eluting Implant in Revision Draf Type III Frontal Sinus Surgery

The Laryngoscope, Volume 136, Issue 9, Page 3732-3736, September 2026.
This technical note introduces a novel endoscopic strategy that integrates a laterally based endonasal mucosal flap with a bioabsorbable steroid‐eluting implant to prevent restenosis following revision of Draf type III frontal sinus surgery. The vascularized flap is stabilized and maintained in close apposition to the underlying bone by a self ...
Mario Turri‐Zanoni, Gloria Schiavo, Marco Valentini, Andrea Presta, Federico Russo, Alessandro Vinciguerra, Paolo Battaglia   +6 more
wiley   +1 more source

Nanoliposome as a carrier for topical delivery of oxymetazoline hydrochloride: In-vitro assessment and in-vivo anti-inflammatory potential

Intelligent Pharmacy
The present investigation on nanoliposome infused with oxymetazoline hydrochloride was fabricated with phosphatidylcholine and cholesterol to effectively deliver the drug to the skin.
Banhishikha Kar, Beduin Mahanti, Ayan Kumar Kar, Subhabrota Majumdar   +3 more
doaj   +1 more source

Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing

The Laryngoscope, Volume 136, Issue 9, Page 3841-3848, September 2026.
This study validates a blue light laser method for assessing laryngeal somatosensory function by measuring perceptual thresholds, reflexive responses, discrimination acuity, and vocal perturbations in healthy adults. Results demonstrate that the method provides precise, reliable stimulation and yields quantifiable sensory and acoustic responses ...
Adrianna C. Shembel, Ted Mau, Youri Maryn, Elizabeth Young, Julianna Smeltzer, Lesley Childs, Shumon Dhar   +6 more
wiley   +1 more source

Association of Nasal and Inhalant Corticosteroids With Pediatric Perioral Dermatitis: A TriNetX Retrospective Cohort Study

Pediatric Dermatology, Volume 43, Issue 5, Page 1158-1162, September/October 2026.
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle, Caitlyn Curley, Dylan Wambold, Basira Iginla, Erum N. Ilyas   +4 more
wiley   +1 more source

Volumetric Absorptive Microsampling During Spaceflight for Analysis of Acetaminophen Pharmacokinetics in Whole Blood

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Spaceflight induces altered physiology that has the potential to alter medication pharmacokinetics due to factors including gastrointestinal motility, fluid balance, circulatory dynamics, hormonal changes, and metabolic alterations. Here, we report the first pharmacokinetic analysis using blood samples during spaceflight.
David Mampre, Robert Guttendorf, Jennifer Zimmer, Brooke Whitson, James Huggins, Chad Christianson, Erik Burns, Nicolas Heft, Marissa Rosenberg, Amran Asadi, Jaime Mateus, James Rudge, Takako Mizuno, John Donehoo   +13 more
wiley   +1 more source

Platelet‐Rich Fibrin Can Improve Septoplasty Results: A Prospective Randomised Controlled Trial

Clinical Otolaryngology, Volume 51, Issue 4, Page 548-554, July 2026.
ABSTRACT Aim This study aims to assess the impact of platelet‐rich fibrin (PRF) on nasal mucociliary clearance (NMC) time and post‐operative pain following septoplasty. Patients and Methods This trial was conducted involving patients who underwent septoplasty. Participants were randomly assigned to either a control group or a PRF group.
Emre Solguntekin, Sedat Çağlı, Kerem Kökoğlu, Emrah Gülmez   +3 more
wiley   +1 more source

Adrenergic Contraction of Human Prostate Tissues Is Maintained Under the Rab GTPase Inhibitors Nexhinib20 and CID1067700 [PDF]

Pharmacol Res Perspect
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Troffer L, Cen P, Brandstetter M, Xu Y, Keller P, Stadelmeier L, Weinhold P, Tamalunas A, Stief C, Hennenberg M.   +9 more
europepmc   +2 more sources

Oxymetazoline Inhibits and Resolves Inflammatory Reactions in Human Neutrophils

Journal of Pharmacological Sciences, 2009
.: The nasal decongestant oxymetazoline (OMZ) exhibits anti-oxidative and antiinflammatory properties (I. Beck-Speier et al., J Pharmacol Exp Ther. 2006;316:842–851).
Ingrid Beck-Speier, Barbara Oswald, Konrad L. Maier, Erwin Karg, René Ramseger   +4 more
doaj   +1 more source

Evaluation of the effects on nasal mucociliary clearance of various nasal solutions applied topically in patients with sinusitis

Medicine Science, 2018
Mucociliary clearance (MC) is one of the main defense mechanisms of the nasal respiratory mucosa. The purpose of this study was to determine changes occurring nasal MC in patients with sinusitis, and how medical treatment affects changes in MC, and to ...
Murat Yasar, Mehmet Yavuz Sutbeyaz, Muhammed Sedat Sakat, Korhan Kilic   +3 more
doaj   +1 more source

Efficacy and usability of a novel nebulizer targeting both upper and lower airways

Italian Journal of Pediatrics, 2017
Background Upper and lower airways diseases share in part their pathogenic mechanisms and frequently occur simultaneously as “United Airway Disease.” Local treatment with nebulizers delivers anti-symptomatic drugs in either the upper or the lower airways,
Daniela Posa, Antonio Pizzulli, Petra Wagner, Serena Perna, Stephanie Hofmaier, Paolo Maria Matricardi, Susanne Lau   +6 more
doaj   +1 more source