Results 21 to 30 of about 10,829 (193)
25-Hydroxycholesterol-Induced Oxiapoptophagy in L929 Mouse Fibroblast Cell Line
Molecules, 2021 25-hydroxycholesterol (25-HC) is an oxysterol synthesized from cholesterol by cholesterol-25-hydroxylase during cholesterol metabolism. The aim of this study was to verify whether 25-HC induces oxiapoptophagy in fibroblasts.
Jae-Seek You +11 more
doaj +1 more source
Cells, 2019 7-Ketocholesterol (7-KC) is a cholesterol oxidation product with several biological functions. 7-KC has the capacity to cause cell death depending on the concentration and specific cell type.
Jessica Liliane Paz +8 more
doaj +1 more source
The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer’s Disease
Antioxidants, 2021 The development of Alzheimer’s disease (AD) is influenced by several events, among which the dysregulation of cholesterol metabolism in the brain plays a major role.
Paola Gamba +7 more
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Metabolic Control of Innate Lymphoid Cell Migration
Frontiers in Immunology, 2019 Innate lymphoid cells (ILCs) are specialized immune cells that rapidly respond to environmental challenges, such as infection and tissue damage. ILCs play an important role in organ homeostasis, tissue repair, and host defense in the mucosal tissues ...
Tim Willinger
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Determination of Pharmaceuticals, Heavy Metals, and Oxysterols in Fish Muscle
Molecules, 2021 The present study aimed to assess the levels of 98 multi-class pharmaceuticals including cardiovascular drugs, antidepressants, hypnotics, antibiotics, and sulfonamides occurring in the muscle tissue of fish caught in the Baltic Sea.
Barbara Bobrowska-Korczak +5 more
doaj +1 more source
Journal of Lipid Research, 2009 Side chain oxysterols are cholesterol derivatives thought to signal the abundance of cell cholesterol to homeostatic effector proteins. Here, we investigated how plasma membrane (PM) cholesterol might regulate 27-hydroxycholesterol (HC) biosynthesis in ...
Yvonne Lange +5 more
doaj +1 more source
Journal of Lipid Research, 2021 Oxysterols are oxidized derivatives of cholesterol that play regulatory roles in lipid biosynthesis and homeostasis. How oxysterol signaling coordinates different lipid classes such as sterols and triglycerides remains incompletely understood.
Ofer Moldavski +11 more
doaj +1 more source
Arteriosclerosis, Thrombosis, and Vascular Biology, 2002 Oxysterols are oxygenated derivatives of cholesterol that are intermediates or even end products in cholesterol excretion pathways. Because of their ability to pass cell membranes and the blood-brain barrier at a faster rate than cholesterol itself, they are also important as transport forms of cholesterol.
Ingemar, Björkhem, Ulf, Diczfalusy
openaire +2 more sources
A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons
Frontiers in Neuroscience, 2018 Oxysterol analogs that modulate NMDA receptor function are candidates for therapeutic development to treat neuropsychiatric disorders. However, the cellular actions of these compounds are still unclear.
Daniel M. Chen +10 more
doaj +1 more source
Preparation of Oxysterols by C–H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst
Molecules, 2021 Seven mono- and dihydroxycholesterols were prepared by direct C–H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh3)] Cl; bpga = 2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl ...
Yui Fujii +8 more
doaj +1 more source