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The oxytocin paradox [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2014
In 2005, Kosfeld et al. published their now seminal paper showing that intranasal oxytocin (OXT) administration increased interpersonal trust (Kosfeld et al., 2005). This finding spawned broad interest into the effects of OXT on social and emotional behavior in humans (Bos et al., 2012), and its implications for translational medicine (Meyer-Lindenberg
Richard A.I. Bethlehem   +8 more
openaire   +5 more sources

Oxytocin and the microbiome

open access: yesComprehensive Psychoneuroendocrinology, 2023
The mammalian host microbiome affects many targets throughout the body, at least in part through an integrated gut-brain-immune axis and neuropeptide hormone oxytocin. It was discovered in animal models that microbial symbionts, such as Lactobacillus reuteri, leverage perinatal niches to promote multigenerational good health and reproductive fitness ...
Bernard J. Varian   +2 more
openaire   +3 more sources

A Synthesis of Oxytocin [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1965
Abstract N-Carbobenzoxy-S-methoxybenzyl-l-cysteinyl-l-tyrosyl-l-isoleucyl-l-glutaminyl-l-asparagin-yl-S-p-methoxybenzyl-l-cysteinyl-l-prolyl-l-leucylglycinamide (IX) was synthesized by the step-wise elongation method, and highly potent oxytocin was obtained from IX by treatment not only with sodium in liquid ammonia, but also with ...
Shumpei Sakakibara   +3 more
openaire   +3 more sources

A Highly Potent Analogue of Oxytocin, Desamino-oxytocin

open access: hybridJournal of Biological Chemistry, 1962
Derek B. Hope   +2 more
openalex   +3 more sources

Characterization and Expression of Oxytocin and the Oxytocin Receptor

open access: yesMolecular Genetics and Metabolism, 2000
Oxytocin, a nonapeptide hormone and neurotransmitter, is expressed in a variety of tissues, as are its receptors. In vivo, oxytocin acts as a paracrine and/or autocrine mediator of multiple biological effects. These effects are exerted primarily through interactions with G-protein-coupled oxytocin/vasopressin receptors, which, via G(q) and G(i ...
Yuji Kaneko, Hideki Shojo
openaire   +3 more sources

Kuramoto model based analysis reveals oxytocin effects on brain network dynamics [PDF]

open access: yesarXiv, 2021
The oxytocin effects on large-scale brain networks such as Default Mode Network (DMN) and Frontoparietal Network (FPN) have been largely studied using fMRI data. However, these studies are mainly based on the statistical correlation or Bayesian causality inference, lacking interpretability at physical and neuroscience level.
arxiv  

Oxytocin and bone

open access: yesAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2014
One of the most meaningful results recently achieved in bone research has been to reveal that the pituitary hormones have profound effect on bone, so that the pituitary-bone axis has become one of the major topics in skeletal physiology. Here, we discuss the relevant evidence about the posterior pituitary hormone oxytocin (OT), previously thought to ...
Graziana Colaianni   +3 more
openaire   +4 more sources

SERS discrimination of single amino acid residue in single peptide by plasmonic nanocavities [PDF]

open access: yesAngewandte Chemie International Edition, 59, 11423-11431 (2020), 2019
Surface-enhanced Raman spectroscopy (SERS) is a sensitive label-free optical method that can provide fingerprint Raman spectra of biomolecules such as DNA, amino acids and proteins. While SERS of single DNA molecule has been recently demonstrated, Raman analysis of single protein sequence was not possible because the SERS spectra of proteins are ...
arxiv   +1 more source

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