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Oxytocin in pregnancy and the postpartum: relations to labor and its management [PDF]

open access: yesFrontiers in Public Health, 2014
The purpose of this study was to examine variations in endogenous oxytocin levels in pregnancy and postpartum state. We also explored the associations between delivery variables and oxytocin levels.
Marie ePrevost   +10 more
doaj   +4 more sources

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration [PDF]

open access: yesNature Communications, 2014
The regenerative capacity of skeletal muscle declines with age. Previous studies suggest that this process can be reversed by exposure to young circulation; however, systemic age-specific factors responsible for this phenomenon are largely unknown.
Christian Elabd   +2 more
exaly   +3 more sources

Efficacy of Oxytocin in Reducing Blood Loss During Abdominal Myomectomy

open access: diamondProceedings, 2022
Introduction: The drug of choice for preventing postpartum uterine atony and bleeding is oxytocin. Myomectomy is a procedure that may result in substantial bleeding.
Saira Niaz   +3 more
doaj   +3 more sources

Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells [PDF]

open access: green, 1993
Oxytocin and its receptor are found in the corpus luteum in a variety of species, including the human. In the present study we used fura-2 microfluorimetry to investigate whether activation of the oxytocin receptor of cultured human granulosa-lutein ...
Gratzl, Manfred   +4 more
core   +2 more sources

An obligate role of oxytocin neurons in diet induced energy expenditure. [PDF]

open access: yesPLoS ONE, 2012
Oxytocin neurons represent one of the major subsets of neurons in the paraventricular hypothalamus (PVH), a critical brain region for energy homeostasis.
Zhaofei Wu   +7 more
doaj   +6 more sources

The Neurobiology of Love and Pair Bonding from Human and Animal Perspectives

open access: yesBiology, 2023
Love is a powerful emotional experience that is rooted in ancient neurobiological processes shared with other species that pair bond. Considerable insights have been gained into the neural mechanisms driving the evolutionary antecedents of love by ...
Sarah A. Blumenthal, Larry J. Young
doaj   +1 more source

The importance of oxytocin neurons in the supraoptic nucleus for breastfeeding in mice.

open access: yesPLoS ONE, 2023
The hormone oxytocin, secreted from oxytocin neurons in the paraventricular (PVH) and supraoptic (SO) hypothalamic nuclei, promotes parturition, milk ejection, and maternal caregiving behaviors. Previous experiments with whole-body oxytocin knockout mice
Mitsue Hagihara   +2 more
doaj   +1 more source

Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2022
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels   +12 more
doaj   +1 more source

α‐Melanocyte‐stimulating hormone inhibition of oxytocin neurons switches to excitation in late pregnancy and lactation

open access: yesPhysiological Reports, 2022
Oxytocin is secreted into the periphery by magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei (SON and PVN) to trigger uterine contraction during birth and milk ejection during suckling.
Michael R. Perkinson   +5 more
doaj   +1 more source

Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum – a systematic review with implications for the function of the oxytocinergic system

open access: yesBMC Pregnancy and Childbirth, 2023
Background The reproductive hormone oxytocin facilitates labour, birth and postpartum adaptations for women and newborns. Synthetic oxytocin is commonly given to induce or augment labour and to decrease postpartum bleeding.
Sarah Buckley   +11 more
doaj   +1 more source

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