Results 1 to 10 of about 68,077 (266)

Intranasal Oxytocin and Physical Intimacy for Dermatological Wound Healing and Neuroendocrine Stress: A Randomized Clinical Trial. [PDF]

JAMA Psychiatry
Schneider E, Hernández C, Brock R, Eckstein M, Bodenmann G, Heinrichs M, Ehlert U, Läuchli S, Ditzen B.   +8 more
europepmc   +2 more sources

The Neurobiology of Love and Pair Bonding from Human and Animal Perspectives

Biology, 2023
Love is a powerful emotional experience that is rooted in ancient neurobiological processes shared with other species that pair bond. Considerable insights have been gained into the neural mechanisms driving the evolutionary antecedents of love by ...
Sarah A. Blumenthal, Larry J. Young
doaj   +1 more source

The importance of oxytocin neurons in the supraoptic nucleus for breastfeeding in mice.

PLoS ONE, 2023
The hormone oxytocin, secreted from oxytocin neurons in the paraventricular (PVH) and supraoptic (SO) hypothalamic nuclei, promotes parturition, milk ejection, and maternal caregiving behaviors. Previous experiments with whole-body oxytocin knockout mice
Mitsue Hagihara, Kazunari Miyamichi, Kengo Inada   +2 more
doaj   +1 more source

Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening   +12 more
doaj   +1 more source

α‐Melanocyte‐stimulating hormone inhibition of oxytocin neurons switches to excitation in late pregnancy and lactation

Physiological Reports, 2022
Oxytocin is secreted into the periphery by magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei (SON and PVN) to trigger uterine contraction during birth and milk ejection during suckling.
Michael R. Perkinson, Matthew K. Kirchner, Meng Zhang, Rachael A. Augustine, Javier E. Stern, Colin H. Brown   +5 more
doaj   +1 more source

Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum – a systematic review with implications for the function of the oxytocinergic system

BMC Pregnancy and Childbirth, 2023
Background The reproductive hormone oxytocin facilitates labour, birth and postpartum adaptations for women and newborns. Synthetic oxytocin is commonly given to induce or augment labour and to decrease postpartum bleeding.
Sarah Buckley, Kerstin Uvnäs-Moberg, Zada Pajalic, Karolina Luegmair, Anette Ekström-Bergström, Anna Dencker, Claudia Massarotti, Alicja Kotlowska, Leonie Callaway, Sandra Morano, Ibone Olza, Claudia Meier Magistretti   +11 more
doaj   +1 more source

Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits

Frontiers in Neuroscience, 2021
There have been numerous studies in which the biological role of oxytocin in trusting behavior has been investigated. However, a link between oxytocin and trust in humans was discovered only in one early study.
Hirofumi Kurokawa, Yusuke Kinari, Hiroko Okudaira, Kiyotaka Tsubouchi, Yoshimichi Sai, Mitsuru Kikuchi, Haruhiro Higashida, Fumio Ohtake   +7 more
doaj   +1 more source

Salivary and plasmatic oxytocin are not reliable trait markers of the physiology of the oxytocin system in humans

eLife, 2020
Single measurements of salivary and plasmatic oxytocin are used as indicators of the physiology of the oxytocin system. However, questions remain about whether they are sufficiently stable to provide valid trait markers of the physiology of the oxytocin ...
Daniel Martins, Anthony S Gabay, Mitul Mehta, Yannis Paloyelis   +3 more
doaj   +1 more source

Maternal body mass index and oxytocin in augmentation of labour in nulliparous women: a prospective observational study

BMJ Open, 2021
Objective To evaluate oxytocin use for augmentation of labour in relation to body mass index (BMI) on admission to the labour ward, focusing on cumulative oxytocin dose and maximum rate of oxytocin infusion during the first stage of labour.Design ...
Preben Kjølhede, Anna Ramö Isgren, Sara Carlhäll, Marie Blomberg   +3 more
doaj   +1 more source

Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally

Molecular Autism, 2017
Background The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the degree of overgrowth positively ...
Catherine E. Barrett, Thomas M. Hennessey, Katelyn M. Gordon, Steve J. Ryan, Morgan L. McNair, Kerry J. Ressler, Donald G. Rainnie   +6 more
doaj   +1 more source