Skeletal muscle: a significant novel neurohypophyseal hormone-secreting organ [PDF]
, 2019 Vasopressin (arg8-vasopressin) and oxytocin are closely relalated hormones, synthesized as pre-hormones in the magnocellular neurons of the paraventricular Q6 and supraoptic nuclei of the hypothalamus.
Dario Coletti +6 more
core +2 more sources
SERS discrimination of single amino acid residue in single peptide by plasmonic nanocavities [PDF]
Angewandte Chemie International Edition, 59, 11423-11431 (2020), 2019 Surface-enhanced Raman spectroscopy (SERS) is a sensitive label-free optical method that can provide fingerprint Raman spectra of biomolecules such as DNA, amino acids and proteins. While SERS of single DNA molecule has been recently demonstrated, Raman analysis of single protein sequence was not possible because the SERS spectra of proteins are ...
arxiv +1 more source
Trust and Time Preference: Measuring a Causal Effect in a Random-Assignment Experiment [PDF]
arXiv, 2022 Large amounts of evidence suggest that trust levels in a country are an important determinant of its macroeconomic growth. In this paper, we investigate one channel through which trust might support economic performance: through the levels of patience, also known as time preference in the economics literature.
arxiv
Reinforcement Learning for Molecular Dynamics Optimization: A Stochastic Pontryagin Maximum Principle Approach [PDF]
arXiv, 2022 In this paper, we present a novel reinforcement learning framework designed to optimize molecular dynamics by focusing on the entire trajectory rather than just the final molecular configuration. Leveraging a stochastic version of Pontryagin's Maximum Principle (PMP) and Soft Actor-Critic (SAC) algorithm, our framework effectively explores non-convex ...
arxiv
Attachment style moderates the effects of oxytocin on social behaviors and cognitions during social rejection: applying an RDoC framework to social anxiety [PDF]
, 2014 Whereas the DSM categorizes individuals with similar self-reported symptoms, the Research Domain Criteria (RDoC) offers a new approach for classifying mental disorders based on dimensions of observable behaviors and neurobiological measures.
Fang, Angela +3 more
core +1 more source
From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]
, 2016 Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni +3 more
core +2 more sources
Efficacy of misoprostol for the treatment of postpartum hemorrhage: current knowledge and implications for health care planning. [PDF]
, 2016 BackgroundA myriad of interventions exist to treat postpartum hemorrhage (PPH), ranging from uterotonics and hemostatics to surgical and aortic compression devices. Nonetheless, PPH remains the leading cause of maternal mortality worldwide.
Prata, Ndola, Weidert, Karen
core +1 more source
Bifurcations of Emergent Bursting in a Neuronal Network [PDF]
, 2011 Currently we routinely develop a complex neuronal network to explain observed but often paradoxical phenomena based upon biological recordings. Here we present a general approach to demonstrate how to mathematically tackle such a complex neuronal network so that we can fully understand the underlying mechanism.
arxiv +1 more source
Accelerating COVID-19 research with graph mining and transformer-based learning [PDF]
arXiv, 2021 In 2020, the White House released the, "Call to Action to the Tech Community on New Machine Readable COVID-19 Dataset," wherein artificial intelligence experts are asked to collect data and develop text mining techniques that can help the science community answer high-priority scientific questions related to COVID-19.
arxiv
Optimal transport weights for causal inference [PDF]
arXiv, 2021 Imbalance in covariate distributions leads to biased estimates of causal effects. Weighting methods attempt to correct this imbalance but rely on specifying models for the treatment assignment mechanism, which is unknown in observational studies. This leaves researchers to choose the proper weighting method and the appropriate covariate functions for ...
arxiv