Results 11 to 20 of about 146,232 (352)

The oxytocin paradox [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2014
In 2005, Kosfeld et al. published their now seminal paper showing that intranasal oxytocin (OXT) administration increased interpersonal trust (Kosfeld et al., 2005). This finding spawned broad interest into the effects of OXT on social and emotional behavior in humans (Bos et al., 2012), and its implications for translational medicine (Meyer-Lindenberg
Richard A.I. Bethlehem   +8 more
openaire   +4 more sources

Oxytocin and the microbiome

open access: yesComprehensive Psychoneuroendocrinology, 2023
The mammalian host microbiome affects many targets throughout the body, at least in part through an integrated gut-brain-immune axis and neuropeptide hormone oxytocin. It was discovered in animal models that microbial symbionts, such as Lactobacillus reuteri, leverage perinatal niches to promote multigenerational good health and reproductive fitness ...
Bernard J. Varian   +2 more
openaire   +3 more sources

A Synthesis of Oxytocin [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1965
Abstract N-Carbobenzoxy-S-methoxybenzyl-l-cysteinyl-l-tyrosyl-l-isoleucyl-l-glutaminyl-l-asparagin-yl-S-p-methoxybenzyl-l-cysteinyl-l-prolyl-l-leucylglycinamide (IX) was synthesized by the step-wise elongation method, and highly potent oxytocin was obtained from IX by treatment not only with sodium in liquid ammonia, but also with ...
S, SAKAKIBARA   +3 more
openaire   +2 more sources

Oxytocin-Trust Link in Oxytocin-Sensitive Participants and Those Without Autistic Traits

open access: yesFrontiers in Neuroscience, 2021
There have been numerous studies in which the biological role of oxytocin in trusting behavior has been investigated. However, a link between oxytocin and trust in humans was discovered only in one early study.
Hirofumi Kurokawa   +7 more
doaj   +1 more source

Salivary and plasmatic oxytocin are not reliable trait markers of the physiology of the oxytocin system in humans

open access: yeseLife, 2020
Single measurements of salivary and plasmatic oxytocin are used as indicators of the physiology of the oxytocin system. However, questions remain about whether they are sufficiently stable to provide valid trait markers of the physiology of the oxytocin ...
Daniel Martins   +3 more
doaj   +1 more source

Maternal body mass index and oxytocin in augmentation of labour in nulliparous women: a prospective observational study

open access: yesBMJ Open, 2021
Objective To evaluate oxytocin use for augmentation of labour in relation to body mass index (BMI) on admission to the labour ward, focusing on cumulative oxytocin dose and maximum rate of oxytocin infusion during the first stage of labour.Design ...
Preben Kjølhede   +3 more
doaj   +1 more source

Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally

open access: yesMolecular Autism, 2017
Background The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the degree of overgrowth positively ...
Catherine E. Barrett   +6 more
doaj   +1 more source

Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling

open access: yesGut Microbes, 2023
Intestinal microbes impact the health of the intestine and organs distal to the gut. Limosilactobacillus reuteri is a human intestinal microbe that promotes normal gut transit, the anti-inflammatory immune system, wound healing, normal social behavior in
Heather A. Danhof   +4 more
doaj   +1 more source

Barriers and Breakthroughs in Targeting the Oxytocin System to Treat Alcohol Use Disorder

open access: yesFrontiers in Psychiatry, 2022
Development of better treatments for alcohol use disorder (AUD) is urgently needed. One promising opportunity for this development is the potential of targeting the oxytocin peptide system.
Andrey E. Ryabinin, Yangmiao Zhang
doaj   +1 more source

Microbial lysate upregulates host oxytocin [PDF]

open access: yes, 2017
Neuropeptide hormone oxytocin has roles in social bonding, energy metabolism, and wound healing contributing to good physical, mental and social health. It was previously shown that feeding of a human commensal microbe Lactobacillus reuteri (L.
Alm, Eric J.   +13 more
core   +1 more source

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