Results 241 to 250 of about 124,617 (305)

Modification of the myometrial relaxing effect of nifedipine in vitro and in vivo [PDF]

, 2011
Hajagos-Tóth, Judit
core  

OPA1 in MC4R Neurons Regulates Dietary Fat Intake and Body Weight in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Soybean oil intake induces OPA1 expression in hypothalamic MC4R neurons, contributing to adaptive regulation of appetite. MC4R neuron‐specific OPA1 deficiency increases soybean oil consumption and leads to obesity, with a more pronounced effect in females.
Shigenobu Matsumura, Mizuki Fujiwara, Soyoka Horie, Miona Marutani, Eri Nousou, Nanase Iki, Yuka Yamato, Yui Otonashi, Tsutomu Sasaki, Mina Fujitani, Teppei Fujikawa   +10 more
wiley   +1 more source

Biomarkers for complex post-traumatic stress disorder: translational and evolutionary perspectives. [PDF]

Front Psychiatry
Rajkumar RP.
europepmc   +1 more source

Exploring Passive Permeability Profiles of Cyclic Heptapeptide Chemical Space Uncovers Bioactivity of Mortiamide Scaffold Driven by Colloidal Aggregation

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
A comprehensive stereochemical and physicochemical survey of cyclic heptapeptide chemical space reveals that the mortiamide natural product scaffold possesses intrinsically low aqueous solubility and forms amyloid‐like fibril aggregates. Multiple orthogonal assays demonstrate that the observed cytotoxicity arises from colloidal aggregation rather than ...
Jaru Taechalertpaisarn, Alexander Engstrom, Maria Sajimon, Beverley M. Rabbitts, Vitor H. Balasco Serrão, Satoshi Ono, Jevgenij A. Raskatov, Timothy C. Johnstone, R. Scott Lokey   +8 more
wiley   +1 more source

Correction: Nazarloo et al. Oxytocin, Vasopressin and Stress: A Hormetic Perspective. <i>Curr. Issues Mol. Biol.</i> 2025, <i>47</i>, 632. [PDF]

Curr Issues Mol Biol
Nazarloo HP, Kingsbury MA, Lamont H, Dale CV, Nazarloo P, Davis JM, Porges EC, Cuffe SP, Carter CS.   +8 more
europepmc   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Oxytocin - A high-alert medication, even in low doses. [PDF]

Indian J Anaesth
Mohta M, Agarwal R, Kumar V, Pratibha.
europepmc   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, Volume 13, Issue 28, 18 May 2026.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Baseline serum oxytocin and OXTR rs53576 genotype are not predictive of escitalopram response in generalized anxiety disorder. [PDF]

Sci Rep
Xue L, Ni H, Xu S.
europepmc   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source