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Oxytocin, oxytocin-associated neurophysin and the oxytocin receptor in the human prostate

Cell and Tissue Research, 2004
Oxytocin has been implicated in the regulation of prostate growth. However, the cellular localisation of oxytocin in the normal and diseased human prostate is not known. Oxytocin, oxytocin-associated neurophysin and oxytocin receptor were detected by immunohistochemistry in tissues from patients undergoing routine prostatectomy and in normal human ...
Whittington, K   +3 more
openaire   +3 more sources

Oxytocin-induced desensitization of the oxytocin receptor

American Journal of Obstetrics and Gynecology, 2003
The purpose of this study was to characterize the oxytocin-induced desensitization of oxytocin-stimulated rises of intracellular calcium in cultured human myocytes.Culture lines were begun from biopsy specimens of myometrium that had been obtained from women who underwent low transverse cesarean deliveries.
Christopher, Robinson   +3 more
openaire   +2 more sources

Hypothalamus and Oxytocin

Nature, 1958
EVIDENCE has recently been produced that, in the rat, oxytocin is synthesized in the paraventricular nucleus1. After small electrolytic lesions in this region a decrease in the amount of oxytocin was found in the posterior pituitary with no change in its vaso-pressin content.
A W, DUGGAN, G W, REED
openaire   +2 more sources

Oxytocin

Current Biology
Oxytocin is a small, nine amino acid peptide synthesized and released mostly in the brain. It was discovered first as a hormone that facilitates labor and lactation but has since attracted interest for having important roles in social bonding. Although sometimes informally called a 'love hormone', this is erroneous and does not accurately reflect the ...
Winokur, Sarah B.   +3 more
openaire   +4 more sources

Oxytocin and Aggression

2017
The neuropeptide oxytocin (OT) has a solid reputation as a facilitator of social interactions such as parental and pair bonding, trust, and empathy. The many results supporting a pro-social role of OT have generated the hypothesis that impairments in the endogenous OT system may lead to antisocial behavior, most notably social withdrawal or ...
Trynke R, de Jong, Inga D, Neumann
openaire   +2 more sources

The oxytocin receptor

Trends in Endocrinology & Metabolism, 2003
Novel sites of oxytocin receptor expression have recently been detected, including breast cancer cells, bone cells, myoblasts, cardiomyocytes and endothelial cells. These discoveries have greatly expanded the possible spectrum of oxytocin action beyond its classic role as an inducer of uterine contractions and milk ejection.
Hans H, Zingg, Stephane A, Laporte
openaire   +2 more sources

The Use Of Oxytocin

Clinics in Perinatology, 1995
Synthetic oxytocin offers a safe and effective means of producing regular uterine activity and has a fairly large therapeutic index; however, the mild antidiuretic and vasoactive properties of oxytocin increase the risk of water intoxication and hypotension.
J M, Shyken, R H, Petrie
openaire   +2 more sources

Oxytocin and Oxytocin Receptors in Cancer Cells and Proliferation

Journal of Neuroendocrinology, 2004
AbstractThe hypothalamic nonapeptide oxytocin plays a crucial role in many reproductive and behavioural functions. However, in recent years, an additional new role for oxytocin has been identified in neoplastic pathology. In tumours, oxytocin acts as a growth regulator, through the activation of a specific G‐coupled transmembrane receptor, the oxytocin
Bice Chini, Paola Cassoni, Anna Sapino
exaly   +5 more sources

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