Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia [PDF]
, 2012 The nonapeptide oxytocin (OXT) and its receptor (OXTR) have been implicated in social cognition, empathy, emotion and stress regulation in humans. Previous studies reported associations between OXT and OXTR genetic polymorphisms and risk for disorders ...
Brockmann, Eva-Maria +5 more
core +3 more sources
Towards the convergent therapeutic potential of GPCRs in autism spectrum disorders [PDF]
arXiv, 2022 Changes in genetic and/or environmental factors to developing neural circuits and subsequent synaptic functions are known to be a causative underlying the varied socio-emotional behavioural patterns associated with autism spectrum disorders (ASD). Seven transmembrane G protein-coupled receptors (GPCRs) comprising the largest family of cell-surface ...
arxiv
Central oxytocin and food intake: focus on macronutrient-driven reward [PDF]
, 2015 Centrally acting oxytocin (OT) is known to terminate food consumption in response to excessive stomach distension, increase in salt loading, and presence of toxins.
Klockars, Anica +2 more
core +3 more sources
Behavioral and epigenetic consequences of oxytocin treatment at birth. [PDF]
, 2019 Oxytocin is used in approximately half of all births in the United States during labor induction and/or augmentation. However, the effects of maternal oxytocin administration on offspring development have not been fully characterized.
Carter, CS +9 more
core
Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism [PDF]
, 2019 Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social interactions, difficulty with communication, and repetitive behavior patterns. In humans affected by ASD, there is a male pre-disposition towards the
Gould, Georgianna G +7 more
core +2 more sources
Modelling Adaptation through Social Allostasis: Modulating the Effects of Social Touch with Oxytocin in Embodied Agents [PDF]
, 2018 Social allostasis is a mechanism of adaptation that permits individuals to dynamically adapt their physiology to changing physical and social conditions.
Ashby +4 more
core +1 more source
NG peptides: A novel family of neurophysin-associated neuropeptides [PDF]
, 2010 NOTICE: this is the author’s version of a work that was accepted for publication in GENE. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be ...
Bromham +20 more
core +1 more source
Preliminary Evidence That CD38 Moderates the Association of Neuroticism on Amygdala-Subgenual Cingulate Connectivity. [PDF]
, 2020 CD38 genetic variation has been associated with autism spectrum disorders and social anxiety disorder, which may result from CD38's regulation of oxytocin secretion.
Burklund, Lisa J +7 more
core +2 more sources
Intranasal Inhalation of Oxytocin Improves Face Processing in Developmental Prosopagnosia [PDF]
, 2013 Developmental prosopagnosia (DP) is characterised by a severe, lifelong impairment in face recognition. Little work has attempted to improve face processing in these individuals, but intriguingly, recent evidence suggests oxytocin can improve face ...
Bate, Sarah +6 more
core
Regulators of G protein signalling proteins in the human myometrium [PDF]
, 2009 The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Abramow-Newerly +52 more
core +1 more source