Results 21 to 30 of about 180,681 (378)

A Synthesis of Oxytocin [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1965
Abstract N-Carbobenzoxy-S-methoxybenzyl-l-cysteinyl-l-tyrosyl-l-isoleucyl-l-glutaminyl-l-asparagin-yl-S-p-methoxybenzyl-l-cysteinyl-l-prolyl-l-leucylglycinamide (IX) was synthesized by the step-wise elongation method, and highly potent oxytocin was obtained from IX by treatment not only with sodium in liquid ammonia, but also with ...
Shumpei Sakakibara   +3 more
openaire   +3 more sources

Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum – a systematic review with implications for the function of the oxytocinergic system

open access: yesBMC Pregnancy and Childbirth, 2023
Background The reproductive hormone oxytocin facilitates labour, birth and postpartum adaptations for women and newborns. Synthetic oxytocin is commonly given to induce or augment labour and to decrease postpartum bleeding.
Sarah Buckley   +11 more
doaj   +1 more source

Is Oxytocin “Nature’s Medicine”?

open access: yesPharmacological Reviews, 2020
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior. Endogenous oxytocin and stimulation of the oxytocin receptor support patterns of growth, resilience, and ...
C. S. Carter   +11 more
semanticscholar   +1 more source

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

open access: yesMolecular Psychiatry, 2020
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and behavior have steadily increased over the last two decades, stimulating considerable interest in its psychiatric application.
D. Quintana   +5 more
semanticscholar   +1 more source

Roles of Oxytocin in Stress Responses, Allostasis and Resilience

open access: yesInternational Journal of Molecular Sciences, 2021
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for psychosocial behavior and reproductive functions. Oxytocin neurons are activated by various stressful stimuli.
Y. Takayanagi, T. Onaka
semanticscholar   +1 more source

The Role of Mesotocin on Social Bonding in Pinyon Jays [PDF]

open access: yes, 2020
The neuropeptide oxytocin influences mammalian social bonding by facilitating the building and maintenance of parental, sexual, and same‐sex social relationships.
Allaire J.   +14 more
core   +2 more sources

Developmental disruption of amygdala transcriptome and socioemotional behavior in rats exposed to valproic acid prenatally

open access: yesMolecular Autism, 2017
Background The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the degree of overgrowth positively ...
Catherine E. Barrett   +6 more
doaj   +1 more source

Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling

open access: yesGut Microbes, 2023
Intestinal microbes impact the health of the intestine and organs distal to the gut. Limosilactobacillus reuteri is a human intestinal microbe that promotes normal gut transit, the anti-inflammatory immune system, wound healing, normal social behavior in
Heather A. Danhof   +4 more
doaj   +1 more source

Oxytocin administration in neonates shapes hippocampal circuitry and restores social behavior in a mouse model of autism

open access: yesMolecular Psychiatry, 2021
Oxytocin is an important regulator of the social brain. In some animal models of autism, notably in Magel2tm1.1Mus-deficient mice, peripheral administration of oxytocin in infancy improves social behaviors until adulthood. However, neither the mechanisms
A. Bertoni   +14 more
semanticscholar   +1 more source

Maternal body mass index and oxytocin in augmentation of labour in nulliparous women: a prospective observational study

open access: yesBMJ Open, 2021
Objective To evaluate oxytocin use for augmentation of labour in relation to body mass index (BMI) on admission to the labour ward, focusing on cumulative oxytocin dose and maximum rate of oxytocin infusion during the first stage of labour.Design ...
Preben Kjølhede   +3 more
doaj   +1 more source

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