Results 261 to 270 of about 50,893 (309)

Fluoreszenzmarkierte Peptidtracer zur simultanen Aktivierung und Bildgebung des Oxytocinrezeptors

open access: yesAngewandte Chemie, Volume 137, Issue 46, November 10, 2025.
Licht ins Dunkel: Hier präsentieren wir die Entwicklung fluoreszenzmarkierter Peptid‐Tracer, die eine gleichzeitige Visualisierung und Aktivierung des Oxytocinrezeptors – eines G‐Protein‐gekoppelten Rezeptors, der an Gesundheit und Krankheit beteiligt ist – ermöglichen.
Monika Perisic Böhm   +11 more
wiley   +1 more source

Quantification of surface-localized and total oxytocin receptor in myometrial smooth muscle cells. [PDF]

open access: yesHeliyon
Fang Y   +7 more
europepmc   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, Volume 599, Issue 21, Page 3124-3149, November 2025.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Long‐read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Faulty DNA repair and epigenetic regulation contribute to neurodegeneration in Alzheimer's disease. Long‐read sequencing enables analysis of “dark regions” that are difficult to study via traditional sequencing methodologies.
Paulino Ramirez   +8 more
wiley   +1 more source

Brain‐Wide Patterns of CRF Receptor 1 Expression in the Transgenic CRFR1‐Cre‐2a‐tdTom Rat

open access: yesJournal of Comparative Neurology, Volume 533, Issue 11, November 2025.
In this article, we provide an extensive neuroanatomical characterization of a recently generated CRFR1‐Cre‐2A‐tdTomato rat. We show that Cre and tdTomato are expressed in a pattern that closely aligns with previously reported CRFR1 expression patterns.
Douglas S. Engelke   +5 more
wiley   +1 more source

Nicotinic Acetylcholine Receptor Pathways in Cancer: From Psychiatric Clues to Therapeutic Opportunities

open access: yesCancer Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background The prevalence of cancer poses significant challenges to treatment, largely because of drug resistance along with other side effects. Current studies have been investigating the growth factors more than other biologic tumor features, such as neurobiologic features.
Mohammad Hossein Azadi   +3 more
wiley   +1 more source

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