Results 81 to 90 of about 22,717 (253)

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

Addiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka, Francesca Spiga, Tom P. Freeman, Suzanne Nielsen, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +6 more
wiley   +1 more source

The evolution of oxytocin receptor signaling

Oxytocin is a neuromodulator and hormone that helps coordinate a variety of physiological and behavioral functions. Oxytocin exerts its diverse effects by binding to oxytocin receptors throughout the brain and the periphery, which initiates various signaling cascades. The location and distribution of oxytocin receptors can differ between species, which
Alina Irene Sartorius, Constantina Theofanopoulou, Daniel S Quintana   +2 more
openaire   +1 more source

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson, Thomas Parkhouse, Chloe Burke, Monika Halicka, Jennifer C. Palmer, Hend Gabr, Rebecca Wilson, Katie E. Webster, Francesca Spiga, Sarah Dawson, Deborah M. Caldwell, Jennifer Scott, Julian P. T. Higgins, Jelena Savović   +13 more
wiley   +1 more source

PROSPECT guideline for total hip arthroplasty: updated systematic review and procedure‐specific postoperative pain management recommendations

Anaesthesia, EarlyView.
Summary Introduction The Procedure Specific Postoperative Pain Management (PROSPECT) collaboration develops evidence‐based recommendations integrating analgesic efficacy, safety and functional recovery. Since publication of the 2021 PROSPECT guidelines for total hip arthroplasty, new evidence, particularly on motor‐sparing regional techniques, has ...
Michele Carella, Dario Bugada, Marc Van de Velde, Helene Beloeil, Eric Albrecht, Patricia Lavandhomme, Johan Raeder, Girish P. Joshi, on behalf of the PROSPECT Working Group of the European Society of Regional Anesthesia and Pain Therapy   +8 more
wiley   +1 more source

Impact of oxytocin discontinuation on fetal heart rate and uterine contractility: A pre‐specified ancillary analysis embedded within a randomized trial

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The impact of oxytocin discontinuation at the onset of the active phase of labor on fetal heart rate (FHR) patterns and uterine activity; One hour following discontinuation, the mean FHR baseline slightly increased, FHR patterns improved—particularly with reduced decelerations and improved variability—and uterine activity decreased. Moreover, among the
Lise Lafforgue, Aude Girault, Loïc Sentilhes, Raoul Desbriere, Diane Korb, Tiphaine Barjat, Camille Le Ray, Charles Garabedian   +7 more
wiley   +1 more source

Transumbilical laparoendoscopic single‐site surgery versus conventional multi‐port laparoscopy for myomectomy: A large single‐center retrospective study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This retrospective observational study compared clinical outcomes from patients who underwent transumbilical laparoendoscopic single‐site surgery (single‐site laparoscopy) or conventional multi‐port laparoscopy for myomectomy. Single‐site laparoscopy and multi‐port laparoscopy showed similar performance in terms of surgical safety.
Xu Yang, Hong Liao, Hongyu Jin, Fan Yang, Sijing Chen, Yu Chen, Jianhong Liu, Xiaorong Qi, Kana Wang, Jinke Li, Qiao Wang, Ying Zheng   +11 more
wiley   +1 more source

Reunion with a peer partner reduces PVN oxytocin neuron immunoreactivity in socially selective voles

Scientific Reports
Friendships—i.e. selective peer relationships—are an important aspect of human behavior, but are rare in rodent species. Meadow voles are seasonally social rodents that form non-reproductive social groups in winter/short day lengths that are selective in
Nastacia L. Goodwin, Al M. Licata, Kelley C. Power, Kara M. Reitz, Yasmin Kamal, Annaliese K. Beery   +5 more
doaj   +1 more source

Vacuum‐assisted hemorrhage control device versus uterine balloon tamponade for refractory atonic postpartum hemorrhage in a protocol‐driven care pathway—A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective cohort study, the vacuum‐assisted hemorrhage‐control device for refractory postpartum hemorrhage, implemented within an E‐MOTIVE and ROTEM‐guided protocol, was associated with reduced transfusion requirements, decreased device indwelling time, fewer high‐dependency admissions, and a shorter duration of hospital stay compared to ...
Kelvin Z. X. Lee, Calista L. S. Por, Tak Yein Lim, Pradip Dashraath, Wei Wei Teo, Christopher King, Su Wei Bryan Ng, Harshaana Ramlal, Liang Shen, Arijit Biswas, Ganesh Acharya, Sabaratnam Arulkumaran, Mahesh Choolani, Sarah W. L. Li   +13 more
wiley   +1 more source

PARTO PREMATURO ASOCIADO A COLESTASIA INTRAHEPATICA DEL EMBARAZO: ROL DEL ACIDOCOLICO EN LA MODULACION DE LA VIA OCITOCINA-RECEPTOR DE OT EN EL MIOMETRIO

Revista Chilena de Obstetricia y Ginecología, 2002
Se ha reportado una asociación entre CIE y distrés fetal, muerte fetal in utero y síntomas de parto prematuro/parto prematuro. Con la hipótesis que en la CIE el aumento en los ácidos biliares, en particular ácido cólico, activa la vía ocitocina-receptor ...
Alfredo M. Germain A., Sumie Kato, Gloria Valdés, Jorge Carvajal, Juan Carlos Glasinovic   +4 more
doaj