Use of a multifocal electroretinogram to evaluate the therapeutic effect of a single intravitreal dexamethasone implant, Ozurdex<sup>®</sup>, for refractory diabetic macular oedema. [PDF]
Mohammed ARA +3 more
europepmc +1 more source
Effectiveness of aflibercept, ranibizumab, and Ozurdex for treating diabetic macular edema showing a suboptimal response: A comparative observational study. [PDF]
Chassid O +6 more
europepmc +1 more source
Subconjunctival dexamethasone implant (Ozurdex<sup>®</sup>) in the management of refractory Non-Infectious anterior scleritis. [PDF]
Ganbold B +21 more
europepmc +1 more source
Back of the Eye Drug Delivery: Advances, Challenges, and Emerging Opportunities for Transformative Therapies. [PDF]
Chauhan A, Kompella U.
europepmc +1 more source
Intravitreal Corticosteroids in the Management of Refractory Macular Edema in Birdshot Chorioretinopathy. [PDF]
Alves Ambrósio J +5 more
europepmc +1 more source
Comprehensive analysis of RS1 gene mutations and clinical manifestations in nine unrelated X-linked retinoschisis (XLRS) Chinese families. [PDF]
Xing D +9 more
europepmc +1 more source
Causes of Visual Loss in Uveitis: A Retrospective Study at a Tertiary Referral Centre. [PDF]
Al-Roubaie M, Beare N.
europepmc +1 more source
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Reverse Engineering the Ozurdex Dexamethasone Intravitreal Implant
International Journal of Pharmaceutics, 2023Ozurdex is a biodegradable implant formulated for sustained-release delivery of the corticosteroid dexamethasone to the posterior segment of the eye. The small, rod-shaped implant is administered directly to the vitreous using a dedicated applicator, and releases drug for up to 6 months after administration.
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Macular edema (ME) is the leading cause of visual loss in uveitis and may persist long after ocular inflammation has been resolved. Local steroids are the first line treatment for uveitis and uveitic ME.
Horace Massa, Georgios D Panos
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