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Exposure to DDT metabolitep,p′-DDE increases autoimmune type 1 diabetes incidence in NOD mouse model
Marina Cetkovic-Cvrlje
exaly +2 more sources
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Science of the Total Environment, 2019
BACKGROUND Although p,p'‑DDT (1,1,1‑trichloro-2,2‑bis (p‑chlorophenyl)‑ethane) has been banned for decades in most countries, its major metabolite p,p'-DDE (1‑dichloro‑2,2‑bis (p‑chlorophenyl) ethylene) is still detected in the vast majority of human ...
M. Koureas +7 more
semanticscholar +1 more source
BACKGROUND Although p,p'‑DDT (1,1,1‑trichloro-2,2‑bis (p‑chlorophenyl)‑ethane) has been banned for decades in most countries, its major metabolite p,p'-DDE (1‑dichloro‑2,2‑bis (p‑chlorophenyl) ethylene) is still detected in the vast majority of human ...
M. Koureas +7 more
semanticscholar +1 more source
Environmental Pollution Series A, Ecological and Biological, 1986
Abstract It is generally accepted that p , p ′-DDE causes many species of bird to lay eggs with thinner shells, but the published evidence for this proposition is ambiguous. Data on egg size (measured by maximum length), shape (measured by the ratio of maximum breadth to maximum length), shell thickness (measured indirectly by Ratcliffe's index, I ...
F. Moriarty, A.A. Bell, H. Hanson
openaire +1 more source
Abstract It is generally accepted that p , p ′-DDE causes many species of bird to lay eggs with thinner shells, but the published evidence for this proposition is ambiguous. Data on egg size (measured by maximum length), shape (measured by the ratio of maximum breadth to maximum length), shell thickness (measured indirectly by Ratcliffe's index, I ...
F. Moriarty, A.A. Bell, H. Hanson
openaire +1 more source
Persistence and binding of p,p'-DDE in soil
Journal of Environmental Science and Health, Part B, 1994Abstract Soil was treated with 14C‐p,p'‐DDE and left under field conditions for 545 days. The dissipation of the chemical was apparently biphasic; halflife of dissipation 271 days. After one year, 61% of the initially applied radiocarbon was lost from soil.
H. C. Agarwal, D. K. Singh, V. B. Sharma
openaire +1 more source
Toxicology Letters, 2018
The hypothesis of fetal origins unraveled that environmental exposures in early life could alter epigenetic modifications in the male germ-line, increasing the susceptibility to adult-onset diseases for generations.
Yang Song, Lei Yang
semanticscholar +1 more source
The hypothesis of fetal origins unraveled that environmental exposures in early life could alter epigenetic modifications in the male germ-line, increasing the susceptibility to adult-onset diseases for generations.
Yang Song, Lei Yang
semanticscholar +1 more source
Residues of p,p′-DDE and mercury in lake trout as a function of age
Archives of Environmental Contamination and Toxicology, 1992Lake trout (Salvelinus namaycush) of known age from 1 to 12 years were taken from Cayuga Lake in central New York State in 1991 and p,p'-DDE and mercury were determined in their flesh. The concentrations of p,p'-DDE and mercury increased significantly (p less than 0.001) with increasing age of the fish.
W H, Gutenmann +4 more
openaire +2 more sources
Science of the Total Environment, 2018
Over the past 20 years, the global incidence of chronic kidney disease (CKD) has been increasing and organochlorine pesticides (such as DDT) is a suspected etiological factor.
S. Jayasinghe +4 more
semanticscholar +1 more source
Over the past 20 years, the global incidence of chronic kidney disease (CKD) has been increasing and organochlorine pesticides (such as DDT) is a suspected etiological factor.
S. Jayasinghe +4 more
semanticscholar +1 more source
Transplacental and Lactational Transfer of p,p′-DDE in Sprague–Dawley Rats
Toxicology and Applied Pharmacology, 1999p,p'-DDE (hereafter DDE), a persistent metabolite of p,p'-DDT, is a widespread environmental contaminant that can induce antiandrogenic developmental effects in rats. Quantitative measurements of the transfer of DDE from pregnant or lactating dams to the fetus or suckling neonate were performed, and physiologically based pharmacokinetic (PBPK) models ...
L, You +5 more
openaire +2 more sources
Transcriptome signatures of p,p´-DDE-induced liver damage in Mus spretus mice.
Environmental Pollution, 2018The use of DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane) in some countries, although regulated, is contributing to an increased worldwide risk of exposure to this organochlorine pesticide or its derivative p,p'-DDE [1,1-dichloro-2,2-bis(p ...
Noelia Morales-Prieto +3 more
semanticscholar +1 more source
Adipose tissue concentrations of p,p′-DDE and the risk for endometrial cancer
Gynecologic Oncology, 2004To evaluate in a case-control study possible risk of endometrial cancer associated with environmental endocrine disruptors.We analyzed the adipose tissue concentrations of polychlorinated biphenyls, hexachlorobenzene (HCB), p,p'-dichlorodiphenyl-dichloroethylene (p,p'-DDE), chlordanes, and polybrominated biphenyls in 76 cases with endometrial cancer ...
Lennart, Hardell +7 more
openaire +2 more sources

