Results 211 to 220 of about 461,399 (248)

Comparative Evaluation of USG, CT, and MRI in Acute Pancreatitis.

J Pharm Bioallied Sci
Karim S, Shukla AK, Sharma AK, Yadav S.
europepmc   +1 more source

Primary Pancreatic Extra-Nodal Natural Killer T-Cell Lymphoma Presenting as Recurrent Acute Pancreatitis. [PDF]

ACG Case Rep J
Blumrosen C, Mitchell N, Syposs C, Kothari T.   +3 more
europepmc   +1 more source

Mucoviscidosis [PDF]

, 1962
Farrerons Có, Javier
core  

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Pancreatic Intraductal Papillary Mucinous Neoplasm Arising Within Heterotopic Pancreas Tissue of the Stomach. [PDF]

ACG Case Rep J
Worapongpaiboon R, Tiankanon K, Mazer BL, Ngamruengphong S.   +3 more
europepmc   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

Use of Teplizumab to Modulate Stage 2 Type 1 Diabetes in Two Individuals With Autoimmune Polyendocrine Syndrome 1. [PDF]

Diabetes Care
Wilson CS, Falk A, Williams JM, Hilmes M, Ross J, LeStourgeon L, Haller MJ, Drawdy M, Pechacek J, Webb T, Diaz-Thomas A, Russell WE, Gregory JM, Virostko J, Lionakis MS, Moore DJ.   +15 more
europepmc   +1 more source

Donaciones rentadas [PDF]

, 2010
Alemán Páez, Francisco
core  

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Surgical Treatment Options for Renal Cell Carcinoma Metastases to the Pancreas-25 Years of Single-Center Experience. [PDF]

Cancers (Basel)
Gajda M, Grudzińska E, Szmigiel P, Sasiński P, Mrowiec S.   +4 more
europepmc   +1 more source