Results 91 to 100 of about 551,283 (346)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Technical options used in pancreatic transplants in brazilian centers [PDF]

, 2005
BACKGROUND: To analyze the profile of the most important Brazilian Transplant Centers regarding technical options in the pancreas transplant. METHODS: A query was sent by electronic mail for the 12 Brazilian Transplant Centers with at least one pancreas ...
Gonzalez, Adriano Miziara, Lopes Filho, Gaspar de Jesus, Melaragno, Claudio, Messetti, Fabrízio, Rangel, Erika Bevilaqua, Triviño, Tarcísio   +5 more
core   +2 more sources

OPTN/SRTR 2016 Annual Data Report: Pancreas

American Journal of Transplantation, 2018
The number of pancreas transplants performed in the United States increased by 7.0% in 2016 over the previous year, the first such increase in more than a decade, largely attributable to an increase in simultaneous kidney pancreas transplants. Transplant
Raja Kandaswamy, Peter G. Stock, S. Gustafson, M. Skeans, M. A. Curry, M. Prentice, A. Fox, A. Israni, J. Snyder, Bertram Kasiske   +9 more
semanticscholar   +1 more source

Neoplasia papilar cístico-sólida de pâncreas

Revista do Colégio Brasileiro de Cirurgiões
The papillary cystic and solid tumor of the pancreas is rare. It occurs predominantly in young women and most present a benign behavior. The most common clinical sign is a large palpable abdominal mass.
Gerson Alves Pereira Júnior, Luis D. Silva Stracieri, Paulo César Espada, José Ivan de Andrade, Reginaldo Ceneviva   +4 more
doaj   +1 more source

MICOFENOLATO DE MOFETIL VS MICOFENOLATO DE SÓDIO APÓS TRANSPLANTE SIMULTÂNEO DE PÂNCREAS-RIM (TSPR)

Brazilian Journal of Transplantation, 2009
Objetivos: Os sintomas gastrointestinais são freqüentes após o uso de derivados do ácido micofenólico. Os objetivos do trabalho foram relatar a incidência de diarréia aguda e descrever os fatores de risco associados a sua ocorrência após o transplante ...
Erika Bevilaqua Rangel, Cláudio Santiago Melaragno, João Roberto de Sá, Adriano Miziara Gonzalez, Marcelo Moura Linhares, Alcides Salzedas, Osmar Medina-Pestana   +6 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Nanopartículas lipídicas na promoção da absorção oral de fármacos [PDF]

, 2013
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasÉ do conhecimento geral que a via oral é a preferida pelos doentes, conduzindo a uma maior ...
Pinto, Sandra Sofia Amaral
core  

Abdominal and pelvic ultrasonography in healthy golden retriever dogs, carriers and affected by gradual muscular dystrophy [PDF]

A distrofia muscular de Duchenne (DMD) é um tipo de distrofia muscular em humanos caracterizada por uma doença genética ligada ao cromossomo X. O cão golden retriever portador da distrofia muscular (GRMD) tem sido intensamente estudado e considerado o ...
ALVES, Flávio Ribeiro, AMBRÓSIO, Carlos Eduardo, FADEL, Leandro, FEITOSA, Matheus Levi Tjara, GRANDO, Angélica Paula, KANAYAMA, Luciane Maria, MARIANA, Arani Nanci Bonfim, MARTINS, Daniele dos Santos, MIGLINO, Maria Angélica, MORINI, Adriana Caroprezo, SANTOS, Juliana Passos Alves dos, STERMAN, Franklin Almeida, ZATZ, Mayana   +12 more
core   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Lesões císticas do pâncreas: uma revisão da literatura

Revista de Medicina da UFC, 2017
Atualmente no Brasil cresce o número de diagnósticos incidentais de tumores císticos de pâncreas em pacientes submetidos a exames de imagem com outra indicação. As neoplasias císticas do pâncreas podem ser divididas principalmente em cistoadenoma seroso,
Helmano Fernandes Moreira Filho, Annya Costa Araújo de Macedo Goes   +1 more
doaj   +1 more source