Results 101 to 110 of about 551,283 (346)

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

PLASMAFÉRESE E TRANSPLANTE DE PÂNCREAS

Hematology, Transfusion and Cell Therapy
Diabetes é a doença pandêmica da era moderna e o número de pessoas diagnosticadas com diabetes tem aumentado. O transplante de pâncreas (TP) pode ser considerado uma oportunidade para manter a normoglicemia com total independência de insulina e é o único
JR Luzzi, MP Miranda, FR Danziere, AEP Ferreira, RANX Plazza, EMB Merchan, CC Borba   +6 more
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Condutas cirúrgicas na úlcera duodenal perfurada (18 casos). [PDF]

, 1982
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Zanelato, Eliana Maris Stella
core  

Lipoma da cabeça do pâncreas

Revista do Colégio Brasileiro de Cirurgiões
Intrapancreatic lipoma is an extremely rare neoplasm. The authors present a case of pancreatic lipoma in a 51-years-old white female, with a history of abdominal pain for a twelve-month period, without other findings.
José Huygens Parente Garcia, Leonardo Mesquita Sampaio, Denissa Ferreira Gomes Vasconcelos   +2 more
doaj   +1 more source

NEUROARTROPATIA DE CHARCOT APÓS O TRANSPLANTE SIMULTÂNEO DE PÂNCREAS-RIM (TSPR)

Brazilian Journal of Transplantation, 2008
A neuroartropatia de Charcot foi inicialmente descrita na Tabes Dorsalis, mas ocorre com mais freqüência em pacientes diabéticos. Sua patogênese inclui (a) neuropatia sensorial; perda da sensibilidade levando a micro-fraturas de repetição, (b ...
Erika Bevilaqua Rangel, Samirah Abreu Gomes, João Roberto de Sá, Cláudio Santiago Melaragno, Aluízio Carvalho, Alcides Salzedas, Marcelo Moura Linhares, Adriano Miziara Gonzalez, José Osmar Medina-Pestana   +8 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Neoplasia papilar cística do pâncreas

Revista do Colégio Brasileiro de Cirurgiões
Papyllary cystic tumor of the pancreas, so-called Frantz's tumor, is rare. Clinical presentation of this disease is usually a slowly growing abdominal mass with or without abdominal pain, affecting predominantly young females.
Francisco Edilson Leite Pinto Junior, Marcus Vinícius de Moraes, Álisson Giovani Freitas de Oliveira   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Simultaneous left colectomy and standard hepatectomy reformed by laparoscopy [PDF]

, 2011
As abordagens laparoscópicas têm sido cada vez mais utilizadas em pacientes com câncer colorretal ou hepático. Colectomia e hepatectomia simultâneas são consideradas técnicas seguras e apresentam resultados oncológicos semelhantes independente da ...
HERMAN, Paulo, LUPINACCI, Renato Arioni, LUPINACCI, Renato Micelli, MACHADO, Marcel Autran   +3 more
core   +1 more source