Results 131 to 140 of about 429,978 (249)

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Comparison of "Continuous" and "End-ischemic" Approaches of Oxygenated Hypothermic Machine Perfusion for Pancreas Preservation. [PDF]

Transplant Direct
Elzawahry MAME, Fallon J, Hastoy B, Lo Faro ML, Nawaz S, Branchereau J, Clark A, Friend P, Ploeg R, Hunter J.   +9 more
europepmc   +1 more source

OBSTRUÇÃO DA FLEXURA ESPLÊNICA DO CÓLON POR NEOPLASIA MALIGNA DE CAUDA DO PÂNCREAS

, 2018
Mabel Cristhina Rodrigues da Silveira, Margarida Maria Fernandes da Silva Moraes, Daniel Ferracioli Brandão, Marley Ribeiro Feitosa, Rogério Serafim Parra, Omar Féres, José Joaquim Ribeiro da Rocha   +6 more
openalex   +1 more source

Contribuição da ultra-sonografia intra-operatória (USIO) no estudo das características anátomo-sonográficas do leiomiossarcoma primário de pâncreas: nota prévia [PDF]

, 2001
Márcio Martins Machado, Ana Cláudia Ferreira Rosa, Marcel Cerqueira César Machado, Sônia Penteado, Giovanni Guido Cerri   +4 more
openalex   +1 more source

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

O pâncreas no alcoólico crónico.

Acta Médica Portuguesa, 1983
C Sofia, M Rosa, L Pragana, L Rocha, J G Monteiro   +4 more
doaj   +1 more source

Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [¹⁸F]FP-(+)-DTBZ PET. [PDF]

Front Endocrinol (Lausanne)
Nejati SF, Sadabad FE, Ren R, Huang Y, Bini J.   +4 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Atresia duodenal associada à pâncreas anular em recém-nascido com trissomia do 21: relato de caso

Laura Fernandes Berto, Rodolfo de Melo Nunes, María Flor Barragán Ibáñez, Eduardo Gallon, Henrique Cannever Velho, Rodrigo Frati   +5 more
openalex   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source