Results 51 to 60 of about 429,978 (249)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Linfangioma cístico do pâncreas

Revista do Colégio Brasileiro de Cirurgiões
Lymphangiomas are benign neoplasias of lymphatic tissue, extremely rare in the pancreas. Three lymphangioma types exist: capillary, cavernous and cystic.
Glauco da Costa Alvarez, Marner Lopes da Silveira, Eduardo Militz da Costa   +2 more
doaj   +1 more source

Epidemiologia do câncer de pâncreas na América Latina e no Brasil [PDF]

, 2023
Diego Rodrigues Mendonça e Silva
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

CONVERSÃO DE DRENAGEM ENTÉRICA PARA VESICAL POR FÍSTULA DUODENAL APÓS TRANSPLANTE DE PÂNCREAS

Brazilian Journal of Transplantation, 2005
Objetivo: O transplante de pâncreas constitui o único método capaz de restabelecer por completo o controle glicêmico sem o uso de insulina exógena. A drenagem exócrina do enxerto pancreático permanece em discussão. O objetivo desse relato é expor o caso
Tércio Genzini, Fábio Crescentini, Huda M Noujaim, Matheo Casagrande, Hugo Abensur, Giovanni Scala Marchini, Fábio César Miranda Torricelli, Marcelo Perosa de Miranda   +7 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

MICOFENOLATO DE MOFETIL VS MICOFENOLATO DE SÓDIO APÓS TRANSPLANTE SIMULTÂNEO DE PÂNCREAS-RIM (TSPR)

Brazilian Journal of Transplantation, 2009
Objetivos: Os sintomas gastrointestinais são freqüentes após o uso de derivados do ácido micofenólico. Os objetivos do trabalho foram relatar a incidência de diarréia aguda e descrever os fatores de risco associados a sua ocorrência após o transplante ...
Erika Bevilaqua Rangel, Cláudio Santiago Melaragno, João Roberto de Sá, Adriano Miziara Gonzalez, Marcelo Moura Linhares, Alcides Salzedas, Osmar Medina-Pestana   +6 more
doaj   +1 more source

CARACTERISTICAS RADIOLÓGICAS DA NEOPLASIAS DE PÂNCREAS: REVISÃO DE LITERATURA

, 2023
Brenda Alves Barnabé, Admardo Raniere de Assis Cunha, LUÍSA BOMJARDIM CARVALHO GUIMARÃES   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source