Results 61 to 70 of about 551,283 (346)
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Pancreatite Aguda Necrosante — Caso Clínico [PDF]
Os autores apresentam um caso clínico de Pancreatite Aguda Hemorrágica, de provável etiologia idiopática, numa criança de 10 meses, que se manifestou inicialmente por vómitos, e alteração do estado de consciência e posteriormente por abdómen agudo.
Alves, R+6 more
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Single-Cell Transcriptomics of the Human Endocrine Pancreas
Human pancreatic islets consist of multiple endocrine cell types. To facilitate the detection of rare cellular states and uncover population heterogeneity, we performed single-cell RNA sequencing (RNA-seq) on islets from multiple deceased organ donors ...
Y. Wang+7 more
semanticscholar +1 more source
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh+8 more
wiley +1 more source
Hiperplasia nodular focal de fígado e pancreatite de repetição - relato de caso [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Oliveira, Raphael Silva Remor de
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Introdução: A neoplasia sólida pseudopapilífera do pâncreas - também denominada Tumor de Frantz - é uma doença rara, cada vez mais citada na literatura. Foi primeiramente descrita por Frantz, em 1959, a partir de quatro casos que foram, então, definidos ...
Marcela Resende Sarmento+1 more
doaj +1 more source
Pancreas preservation time as a predictor of prolonged hospital stay after pancreas transplantation
Objective Length of hospital stay is a sensitive indicator of short-term prognosis. In this retrospective study, we investigated how pancreas preservation time affects length of hospital stay after pancreas transplantation.
Shengmin Mei+8 more
doaj +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Ruiz, José A Segura
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Identification and management of pancreas divisum
Introduction: Pancreas divisum is the most common congenital malformation of the pancreas with the majority asymptomatic. The etiological role, pathogenesis, clinical significance and management of pancreas divisum in pancreatic disease has not been ...
A. Gutta, E. Fogel, S. Sherman
semanticscholar +1 more source