Results 61 to 70 of about 429,978 (249)

Neoplasia papilar cístico-sólida de pâncreas

open access: yesRevista do Colégio Brasileiro de Cirurgiões
The papillary cystic and solid tumor of the pancreas is rare. It occurs predominantly in young women and most present a benign behavior. The most common clinical sign is a large palpable abdominal mass.
Gerson Alves Pereira Júnior   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Neoplasia papilar cística do pâncreas

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Papyllary cystic tumor of the pancreas, so-called Frantz's tumor, is rare. Clinical presentation of this disease is usually a slowly growing abdominal mass with or without abdominal pain, affecting predominantly young females.
Francisco Edilson Leite Pinto Junior   +2 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Lipoma da cabeça do pâncreas

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Intrapancreatic lipoma is an extremely rare neoplasm. The authors present a case of pancreatic lipoma in a 51-years-old white female, with a history of abdominal pain for a twelve-month period, without other findings.
José Huygens Parente Garcia   +2 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

PLASMAFÉRESE E TRANSPLANTE DE PÂNCREAS

open access: yesHematology, Transfusion and Cell Therapy
Diabetes é a doença pandêmica da era moderna e o número de pessoas diagnosticadas com diabetes tem aumentado. O transplante de pâncreas (TP) pode ser considerado uma oportunidade para manter a normoglicemia com total independência de insulina e é o único
JR Luzzi   +6 more
doaj   +1 more source

NEUROARTROPATIA DE CHARCOT APÓS O TRANSPLANTE SIMULTÂNEO DE PÂNCREAS-RIM (TSPR)

open access: yesBrazilian Journal of Transplantation, 2008
A neuroartropatia de Charcot foi inicialmente descrita na Tabes Dorsalis, mas ocorre com mais freqüência em pacientes diabéticos. Sua patogênese inclui (a) neuropatia sensorial; perda da sensibilidade levando a micro-fraturas de repetição, (b ...
Erika Bevilaqua Rangel   +8 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Avaliação epidemiológica do Câncer de pâncreas no Brasil: mortalidade e fatores de risco

open access: diamond, 2022
Amanda Gabriela Mora Pereira   +6 more
openalex   +1 more source

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