Results 61 to 70 of about 40,513,033 (232)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

[Report to W. P. Gannaway by T. T. Wardlaw, February 18, 1964 #3]

open access: yes, 1964
Criminal intelligence report by T. T. Wardlaw regarding an interview with Pierce Allman. Allman, who worked at a radio station, was watching the parade with Terrence Ford at the time that the President Kennedy was assassinated.
Dallas (Tex.). Police Department.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Effects of Periodic Normal Stress Oscillations on Frictional Properties of Simulated Natural Fault Gouges Under In Situ P‐T Conditions

open access: yesGeophysical Research Letters
Induced earthquakes are occasionally associated with stress oscillations resulting from periodic industrial activities. Yet, the effects of stress oscillations on fault friction under realistic subsurface conditions are not fully clear.
Bowen Yu   +5 more
doaj   +1 more source

Two-point boundary value problems for 4th order ordinary differential equations

open access: yesMiskolc Mathematical Notes
The new optimal efficient sufficient conditions are established for solvability and uniqueness of a solution of the linear and nonlinear fourth order ordinary differential equations u^(4)(t) = p(t)u(t) + q(t) for t ∈ [a,b], u^(4)(t) = p(t)u(t) + f(t, u(t)
Mariam Manjikashvili   +1 more
doaj   +1 more source

[Report to W. P. Gannaway by T. T. Wardlaw, February 18, 1964 #2]

open access: yes, 1964
Criminal intelligence report by T. T. Wardlaw regarding an interview with Pierce Allman. Allman, who worked at a radio station, was watching the parade with Terrence Ford at the time that the President Kennedy was assassinated.
Dallas (Tex.). Police Department.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Role of Water in the Selection of Stable Proteins at Ambient and Extreme Thermodynamic Conditions

open access: yesPhysical Review X, 2017
Proteins that are functional at ambient conditions do not necessarily work at extreme conditions of temperature T and pressure P. Furthermore, there are limits of T and P above which no protein has a stable functional state.
Valentino Bianco   +3 more
doaj   +1 more source

High-resolution investigation of the Sb-121(p,t)Sb-119 reaction and quasiparticle-phonon model description

open access: yes, 2007
The Sb-121(p,t)Sb-119 reaction has been measured in a high-resolution experiment at an incident energy of 21 MeV. Accurate measurement of the (p,t) reaction angular distributions for the transitions to the levels of Sb-119 allows us to determine energies
P. Guazzoni   +7 more
core   +1 more source

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