Results 81 to 90 of about 40,513,033 (232)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Remediation of Anomia in lvPPA and svPPA
Frontiers in Psychology, 2015 Anomia treatment efficacy has been examined in cases with different subtypes of primary progressive aphasia (PPA), and it has been evaluated in groups of participants with the semantic variant (svPPA), but efficacy has not been examined in groups with ...
Aaron Meyer +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Sign-constancy of Green’s functions for impulsive nonlocal boundary value problems
Boundary Value Problems, 2019 We consider the following second order impulsive differential equation with delays: {(Lx)(t)≡x″(t)+∑j=1paj(t)x′(t−τj(t))+∑j=1pbj(t)x(t−θj(t))=f(t),t∈[0,ω],x(tk)=γkx(tk−0),x′(tk)=δkx′(tk−0),k=1,2,…,r.
A. Domoshnitsky, Iu. Mizgireva
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Standortanalyse der T&P Troxler&Partner AG
, 2018 Die T&P Troxler & Partner AG ist ein dienstleistungsorientiertes Ingenieurunternehmen. Die Unternehmung hat seit 34 Jahren denselben Standort in der Gemeinde Ruswil.
Käch, Jennifer, Troxler, Laila
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Class p-wA(s, t) operators and invariant subspaces
, 2020 In this paper we prove that if T ∈ B(H) is a pure class p-wA(s, t) operator (0 < s, t, s + t = 1 and 0 < p ≤ 1) with dense range such that 0 ∈/ σp(T), then T has a non-trivial invariant subspace if and only if its second generalized Aluthge ...
Prasad T.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source