Results 101 to 110 of about 40,513,033 (232)

[Report to W. P. Gannaway by T. Ingargiola, December 17, 1963 #2]

open access: yes, 1963
Photocopy of a typed report addressed to Captain W. P. Gannaway of the Special Service Bureau in Dallas, Texas. The report, which was submitted by detective T. Ingargiola, lists officers assigned as security guards on the first floor of the Trade Mart on
Dallas (Tex.). Police Department.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Contrasting P-T-t paths for Neoproterozoic metamorphism in MacRobertson and Kemp Lands, east Antarctica

open access: yes, 2007
Mineral equilibria modelling and electron microprobe chemical dating of monazite in granulite facies metapelitic assemblages from the MacRobertson Land coastline, Rayner Complex, east Antarctica, are consistent with an 'anticlockwise' Neoproterozoic P-T ...
Kelsey, DE (15553358)   +3 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

[Report to W. P. Gannaway by T. T. Wardlaw, February 18, 1964 #1]

open access: yes, 1964
Intelligence report to Captain W. P. Gannaway through Lt. Jack Revill concerning Pierce Allman. Mr.
Wardlaw, T. T.
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Discrete Transparent Boundary Conditions for Parabolic Equations

open access: yes, 2007
) = u(0; t); v(\Gamma1; t) = 0; (Tu)(t) := v x (0; t); (2) for x ! 0 and couple it with (1) by the assumption that u, u x are continuous across the artificial boundary at x = 0. Since the initial data vanishes for x !
Transparent Boundary Conditions   +1 more
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Positive solutions for a second-order \Phi-Laplacian equations with limiting nonlocal boundary conditions

open access: yesElectronic Journal of Differential Equations, 2016
Motivated, mainly, by the works of Fewster-Young and Tisdell [9,10] and Orpel [30], as well as the papers by Karakostas [21,22,23], we give sufficient conditions to guarantee the existence of (nontrivial) solutions of the second-order Phi-Laplacian
George L. Karakostas   +2 more
doaj  

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