Results 121 to 130 of about 14,988,203 (289)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 2016 Motivated, mainly, by the works of Fewster-Young and Tisdell [9,10] and Orpel [30], as well as the papers by Karakostas [21,22,23], we give sufficient conditions to guarantee the existence of (nontrivial) solutions of the second-order Phi-Laplacian
George L. Karakostas +2 more
doaj
, 2017 Microporous compounds are a class of open-framework materials; their structures contain cavities (in the form of channels or cages) with free diameters < 2 nm [1].
P. Lotti
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Positive solutions for the one-dimensional Sturm-Liouville superlinear p-Laplacian problem
Electronic Journal of Differential Equations, 2018 We prove the existence of positive classical solutions for the p-Laplacian problem $$\displaylines{ -(r(t)\phi (u'))'=f(t,u),\quad t\in (0,1), \cr au(0)-b\phi ^{-1}(r(0))u'(0)=0,\ cu(1)+d\phi ^{-1}(r(1))u'(1)=0, }$$ where $\phi (s)=|s|^{p-2}s$, $p ...
Khanh Duc Chu, Dang Dinh Hai
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Journal of Inequalities and ApplicationsThis work addresses a value problem concerning a system of high-order nonlinear equations with viscoelastic terms acting in both equations and homogeneous Dirichlet conditions.
Amar Ouaoua +2 more
doaj +1 more source
Application of Thermodynamic Forward-modeling to Estimation of a Metamorphic P-T Path
, 2004 One of the important aims of metamorphic petrology is to unveil the physicochemical conditions of the Earth's interior. Decoding the record of metamorphism is a case of the inverse problem based on observations of stable equilibrium mineral assemblages ...
10437 +3 more
core