Results 141 to 150 of about 14,988,203 (289)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Electronic Journal of Differential Equations, 2003 In this article, we study the differential equation $$ (-1)^{n-p} x^{(n)}(t)=f(t,x(t),x'(t),dots,x^{(n-1)}(t)), $$ subject to the multi-point boundary conditions $$displaylines{ x^{(i)}(0)=0 quad hbox{for }i=0,1,dots,p-1,cr x^{(i)}(1)=0 quad hbox{for }i ...
Yuji Liu, Weigao Ge
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A Generalized Asymmetric Student-t Distribution with Application to Financial Econometrics [PDF]
This paper proposes a new class of asymmetric Student-t (AST) distributions, and investigates its properties, gives procedures for estimation, and indicates applications in financial econometrics.
John Galbraith, Dongming Zhu
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2011 P-T conditions of the Alpine regional metamorphism of carbonate successions which form the cover sequence of the southern Veporicum crystalline basement have been determined.
Vozárová, A. +3 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Electronic Journal of Differential Equations, 2017 In this article we consider the nonlinear Viscoelastic wave equations of Kirchhoff type $$\displaylines{ u_{tt}-M( \| \nabla u\| ^2) \Delta u+\int_0^{t}g_1( t-\tau )\Delta u( \tau ) d\tau +u_t =( p+1)| v| ^{q+1}| u| ^{p-1}u, \cr v_{tt}-M( \| \nabla
Erhan Piskin, Ayse Fidan
doaj