Results 131 to 140 of about 14,988,203 (289)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Distribution patterns of TCIFPnatives of P-IFPs at different H- and T-threshold conditions.

open access: yes, 2013
TCIFPnatives of P-IFPs for all 44 protein pairs were calculated using the indicated H- and T-threshold conditions. At a given H—threshold condition, all T-threshold conditions produced the same line plot.
Yutaka Akiyama (323798)   +4 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

P-T-t-deformation framework of an accretionary prism, southern New England Orogen, eastern Australia: implications for blueschist exhumation and metamorphic switching

open access: yes
The Tia Complex is located in the southern New England Orogen of eastern Australia and provides a detailed record of the structural-metamorphic evolution of an ancient accretionary prism.
Robin Offler (21132722)   +2 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Nonlinear initial-value problems with positive global solutions

open access: yesElectronic Journal of Differential Equations, 2003
We give conditions on $m(t)$, $p(t)$, and $f(t,y,z)$ so that the nonlinear initial-value problem {gather*} frac{1}{m(t)} (p(t)y')' + f(t,y,p(t)y') = 0,quadmbox{for }t>0, y(0)=0,quad lim_{t o 0^+} p(t)y'(t) = B, end{gather*} has at least one positive ...
John V. Baxley, Cynthia G. Enloe
doaj  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

P-T-conditions and origin of mica-schists from Psunj-metamorfic complex outcrops on Papuk [PDF]

open access: yes, 2018
Izdanci psunjskog metamorfnog kompleksa u istoĉnim dijelovima Papuka sadrţe/izgraĊeni su od granat-staurolitnih tinjĉevih škriljavaca. Pojava tih minerala omogućava u povoljnim sluĉajevima rekonstrukciju p-T-metamorfnog puta, a kod nepovoljnih ...
Pilkić, Tomislav
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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