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Solamargine acts as an antiviral by interacting to MZF1 and targeting the core promoter of the hepatitis B virus gene. [PDF]
Aging (Albany NY)Chen W +8 more
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Journal of Chromatography B: Biomedical Sciences and Applications, 1998
A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
Reginald F. Frye +2 more
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A sensitive and specific high-performance liquid chromatographic assay was developed for the simultaneous determination of p-aminohippuric acid (PAH), acetyl-p-aminohippuric acid (aPAH), and iothalamate in human plasma and urine. Plasma samples were prepared by protein precipitation with acetonitrile followed by evaporation, reconstitution in mobile ...
Reginald F. Frye +2 more
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Plasma Clearance of p-Aminohippuric Acid by the Kidneys of Fœtal, Neonatal and Adult Sheep
Nature, 1962AN investigation into the development of secretory activity in the renal tubules has been undertaken using p-aminohippuric acid.
Nixon Da, Alexander Dp
semanticscholar +5 more sources
p-Aminohippuric acid transport into brush border vesicles isolated from flounder kidney
American Journal of Physiology-Renal Physiology, 1979p-Aminohippuric acid (PAH) transport was investigated in brush border vesicles isolated from renal proximal tubules of the winter flounder. Three characteristics of carrier-mediated transport were demonstrated: 1) unlabeled PAH inhibited the uptake of [3H]PAH; 2)[3H]PAH efflux from the vesicles was stimulated in the presence of unlabeled PAH in the ...
Jill Eveloff +2 more
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Journal of Pharmacokinetics and Biopharmaceutics, 1989
Kidney disease is generally thought to affect all segments of a nephron equally. Bricker and co-workers first proposed this as the Intact Nephron hypothesis in 1971, and evidence to date has usually supported this hypothesis. However, most supporting studies have involved severe renal failure, which may not be suitable to differentiate effects on ...
Carol A. Gloff, Leslie Z. Benet
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Kidney disease is generally thought to affect all segments of a nephron equally. Bricker and co-workers first proposed this as the Intact Nephron hypothesis in 1971, and evidence to date has usually supported this hypothesis. However, most supporting studies have involved severe renal failure, which may not be suitable to differentiate effects on ...
Carol A. Gloff, Leslie Z. Benet
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Comparison of renal prostaglandin and p-aminohippuric acid transport processes
American Journal of Physiology-Renal Physiology, 1978R. A. Baroody, Laszlo Z. Bito
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Acta Physiologica Scandinavica, 1970
Abstract20 pigs weighing 21–124 kg were used to determine the clearance of PAH, N4‐acetylated PAH and PAHtotal, and for determination of acetylation of PAH and de‐acetylation of N4‐acetylated PAH in the kidney. By examining blood samples taken from a. renalis and v.
Folke Rasmussen, N. Gyrd-Hansen
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Abstract20 pigs weighing 21–124 kg were used to determine the clearance of PAH, N4‐acetylated PAH and PAHtotal, and for determination of acetylation of PAH and de‐acetylation of N4‐acetylated PAH in the kidney. By examining blood samples taken from a. renalis and v.
Folke Rasmussen, N. Gyrd-Hansen
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Quantitation of P-Aminohippuric Acid and N-Acetyl-P-Aminohippuric Acid from Blood by HPLC
Journal of Liquid Chromatography, 1981Abstract P-aminohippuric acid, N-acetyl-p-aminohippuric acid, and p-aminobenzoic acid can be separated by a reverse-phase, isocratic high-pressure liquid chromatographic procedure in less than 4 minutes. The eluent is 10 mM sodium phosphate buffer, pH 3.5, containing 30% methanol.
J. W. Young +3 more
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RENAL TUBULAR REABSORPTION OF p-AMINOHIPPURIC ACID (PAll) IN THE DOG
The Journal of Pharmacology and Experimental Therapeutics, 1970K C, Cho, E J, Cafruny
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Journal of Separation Science, 2014
p-Aminohippuric acid is a newly developed ligand for mixed-mode chromatography with a commercial resin name of Nuvia cPrime. In this study, bovine immunoglobulin G and bovine serum albumin were used as two model proteins, and the adsorption isotherms ...
Jun Yan +3 more
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p-Aminohippuric acid is a newly developed ligand for mixed-mode chromatography with a commercial resin name of Nuvia cPrime. In this study, bovine immunoglobulin G and bovine serum albumin were used as two model proteins, and the adsorption isotherms ...
Jun Yan +3 more
semanticscholar +1 more source