Results 191 to 200 of about 832,375 (231)
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Biomedical chromotography, 1994
A high-performance liquid chromatographic (HPLC) assay method has been developed for the quantitative determination of iothalamate and p-aminohippuric acid (PAH) concentrations in serum and urine samples in the male rat.
R. R. Bell+6 more
semanticscholar +1 more source
A high-performance liquid chromatographic (HPLC) assay method has been developed for the quantitative determination of iothalamate and p-aminohippuric acid (PAH) concentrations in serum and urine samples in the male rat.
R. R. Bell+6 more
semanticscholar +1 more source
Technetium-99m Labeled p-Aminohippuric Acid Analogues: Renal Function Agents
Journal of Pharmaceutical Sciences, 1989A number of p-aminohippuric acid analogues were synthesized in order to develop clinically useful 99mTc-labeled radiopharmaceuticals for evaluation of renal function measurements. Stable 99mTc-labeled complexes were formed at pH 5.7 using a Sn(II) reduction method with all derivatives.
Kuldeep K. Bhargava+4 more
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Complexation behaviour of tin(II) ion with derivative of p‐aminohippuric acid
Journal of Labelled Compounds and Radiopharmaceuticals, 1994AbstractComplex formation between tin(II) ion and p‐(biscarboxymethyl)‐aminomethyl‐carbamino‐hippuric acid (PAHIDA) in 0.5 M NaClO4 ionic medium at 298 K, was studied by means of u.v. spectrophotometry and glass electrode potentiometric titrations. In the concentration range 0.09 ⩽ [Sn] ⩽ 0.150, 0.5 ⩽ [PAHIDA] ⩽ 3.0 (mmol dm−3) and 1.30 ⩽ pH ⩽ 6.5 ...
Tatjana Maksin+2 more
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A simple liquid chromatography procedure for p-aminohippuric acid in blood serum and urine
Biochemical Medicine, 1975Abstract An extremely simple procedure for determining p-aminohippuric acid (PAH) is described based on liquid chromatographic separation followed by detection via direct electrochemical oxidation in a thin-layer cell. The detection limit for PAH is approximately 100 pg and quantitation is possible with 500 pg injected.
Ronald E. Shoup, Peter T. Kissinger
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Journal of Chromatography B: Biomedical Sciences and Applications, 1997
We report a simple and rapid HPLC procedure for measuring p-aminohippuric acid in serum and urine. After deproteinization with acetonitrile and addition of p-aminobenzoic acid as an internal standard, the chromatographic run is performed on a C18 column with the absorbance detector set at 275 nm.
R. Marsilio+6 more
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We report a simple and rapid HPLC procedure for measuring p-aminohippuric acid in serum and urine. After deproteinization with acetonitrile and addition of p-aminobenzoic acid as an internal standard, the chromatographic run is performed on a C18 column with the absorbance detector set at 275 nm.
R. Marsilio+6 more
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Uptake of uric acid and p-aminohippurate (PAH) by renal cortical slices of various mammals
Comparative Biochemistry and Physiology Part A: Physiology, 19921. Accumulation of uric acid and PAH was measured in renal cortical slices of various mammalian species. 2. The slice to medium ratio of uric acid was above unity in the rabbit, guinea pig, pig and cow, suggesting an active accumulation of uric acid, while it was near or below unity in the rat and mongrel dog. 3.
Jin Sup Jung, Sang Ho Lee, Yong Keun Kim
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Journal of Chromatography B, 2010
A rapid, simple and sensitive method was developed for the determination of para-aminohippuric acid (PAH) in rat plasma using liquid chromatography tandem mass spectrometry (LC-MS-MS). Acetaminophen was used as the internal standard. Chromatographic separation was performed using a Symmetry C18 column and the mobile phase was composed of A: 2 mM ...
Hsien-Yuan Fan+2 more
openaire +2 more sources
A rapid, simple and sensitive method was developed for the determination of para-aminohippuric acid (PAH) in rat plasma using liquid chromatography tandem mass spectrometry (LC-MS-MS). Acetaminophen was used as the internal standard. Chromatographic separation was performed using a Symmetry C18 column and the mobile phase was composed of A: 2 mM ...
Hsien-Yuan Fan+2 more
openaire +2 more sources
Toxicology Letters, 1998
Hexachloro-1:3-butadiene (HCBD) and potassium dichromate (Cr6+) are chemicals toxic for the pars recta and the pars convoluta, respectively. PAH accumulation takes place in the basolateral membrane of the proximal tubule and its impairment is a sign of damage of the membrane.
TREVISAN, ANDREA+5 more
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Hexachloro-1:3-butadiene (HCBD) and potassium dichromate (Cr6+) are chemicals toxic for the pars recta and the pars convoluta, respectively. PAH accumulation takes place in the basolateral membrane of the proximal tubule and its impairment is a sign of damage of the membrane.
TREVISAN, ANDREA+5 more
openaire +3 more sources
Effect of ouabain on renal transport of P-aminohippuric acid (PAH) and blood flow in the dog
European Journal of Pharmacology, 1968Abstract PAH was infused i.v. to establish plasma concentrations of 2 to 48 mg%. Ouabain was given into one renal artery at rates of 0.7 to 1.3 μg/kg/min for 60 to 80 min. In most experiments there was a clear dissociation between the effects of ouabain on PAH and Na + transport indicating a certain selectivity for the cation.
David A. Chinoy, Bohdan R. Nechay
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Renal uptake of p-aminohippuric acid in vitro effects of palmitate and l-carnitine
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1971Abstract 1. 1. The uptake of p- aminohippuric acid by rat renal cortical slices and its relationship to the renal uptake of non-esterified fatty acids was studied. 2. 2. 1 mM palmitate competitively inhibits renal p- aminohippuric acid uptake. 3. 3.
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