Results 21 to 30 of about 10,171 (209)

Synthesis and in vivo evaluation of non-hepatotoxic acetaminophen analogs [PDF]

open access: yes, 2007
A series of acetaminophen (APAP) analogs, 2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)-N-(4-hydroxyphenyl)alkanecarboxamides, bearing a heterocyclic moiety linked to the p-acylaminophenol fragment, were prepared in a general project to develop APAP ...
Bazan, Nicolas G.   +11 more
core   +3 more sources

Kidney Lesions Induced in Rats by P-aminophenol [PDF]

open access: yesBMJ, 1969
Necrosis of the terminal third of the proximal convulated tubule develops in rats after a single intravenous injection of p-aminophenol hydrochloride. As the tubules regenerate a chronic inflammatory reaction occurs in the interstitial tissue, and this reaction extends beyond the original zone of injury. These findings are additional evidence that some
C R, Green, K N, Ham, J D, Tange
openaire   +2 more sources

Urinary Recovery of Salicylamide as Its Glucuronide in Liver Disease [PDF]

open access: yes, 1962
An attempt was made to establish the method for the estimation of glucuronide formation in vivo using salicylamide and further to study the alteration in the glucuronide formation in liver disease. The results were as follows: 1.
Taketa, Kazuhisa
core   +1 more source

Aniline-Hydroxylation Activity of a Flavin-linked βαβα-Type Polypeptide Packing an Iron Porphyrin [PDF]

open access: yes, 2003
Polypeptide containing iron porphyrin and flavin showed aniline-hydroxylation activity in the presence of 1-benzyl-1,4-dihydronicotinamide and O2. The increased activity at pH 5.5 compared with that at pH 7.0 suggests that the dissociation of His from ...
Arai Toru   +4 more
core   +2 more sources

Hydrodynamic Voltammetry as a Rapid and Simple Method for Evaluating Soil Enzyme Activities

open access: yesSensors, 2015
Soil enzymes play essential roles in catalyzing reactions necessary for nutrient cycling in the biosphere. They are also sensitive indicators of ecosystem stress, therefore their evaluation is very important in assessing soil health and quality.
Kazuto Sazawa, Hideki Kuramitz
doaj   +1 more source

Smart chemometrics-assisted spectrophotometric methods for efficient resolution and simultaneous determination of paracetamol, caffeine, drotaverine HCl along with three of their corresponding related impurities

open access: yesBMC Chemistry, 2023
Three novel, simple and accurate multivariate spectrophotometric assisted mathematical techniques were developed for determination of paracetamol, caffeine, drotaverine HCl and their related impurities.
Samia A. Tawfik   +3 more
doaj   +1 more source

Polyaminoanthraquinone Modified Electrodes as Electroanalytical Sensors

open access: yesInternational Journal of Electrochemical Science, 2011
Poly 1-amino-9,10-anthraquinone, PAAQ, films were prepared by the electropolymerization of 1-amino-9,10-anthraquinone, AAQ, on platinum substrates. The polymerization process was carried out in both nonaqueous (Acetonitrile containing 0.1 mole L-1 LiClO4
Waheed A. Badawy   +2 more
doaj   +1 more source

Влияние природы носителя на каталитическую активность наночастиц палладия в реакции гидрирования о-нитротолуола [PDF]

open access: yes, 2017
Изучена каталитическая активность нанокомпозитных материалов на основе нанесенных из коллоидного раствора на активированный уголь, азотсодержащие углеродные нанотрубки, графит и γ-Аl₂О₃ наночастиц палладия в реакции гидрирования о-нитротолуола ...
Бычко, И.Б.   +5 more
core   +2 more sources

Adsorption of Aromatic Compounds from Aqueous Solution by a Hypercrosslinked Polymeric Adsorbent with Sulphonic Groups

open access: yesAdsorption Science & Technology, 2003
A hypercrosslinked polymeric adsorbent with sulphonic groups, NG-5, was employed to remove p -toluidine, p -aminophenol and phenol from aqueous solutions and its performance and thermodynamic behaviour compared to that of the hypercrosslinked polymeric ...
Hai-Ling Wang   +5 more
doaj   +1 more source

NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]

open access: yes, 2014
[Image: see text] The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Ahn K. S.   +45 more
core   +4 more sources

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