p-Cresol induces disruption of cardiomyocyte adherens junctions
Toxicology, 2013 Higher serum levels of p-cresol in chronic kidney disease populations have been associated with increased cardiovascular mortality. However, studies on how p-cresol affects intercellular junctions between cardiomyocytes were limited. This study investigated the effect of p-cresol on adherens junction (AJ) of neonatal cultured cardiomyocytes and its ...
Yu-Sen, Peng +5 more
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Physicochemical data of p-cresol, butyric acid, and ammonia
Data in Brief, 2019 There is a renewed interest in treating odorous contaminants such as butyric acid, p-cresol, and ammonia that are emitted from animal farming operations.
Praveen Kolar +2 more
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Bioenergetic strategy for the biodegradation of p-cresol by the unicellular green alga Scenedesmus obliquus. [PDF]
PLoS ONE, 2012 Cultures from the unicellular green alga Scenedesmus obliquus biodegrade the toxic p-cresol (4-methylphenol) and use it as alternative carbon/energy source. The biodegradation procedure of p-cresol seems to be a two-step process.
Aikaterini Papazi +2 more
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p-Cresol affects reactive oxygen species generation, cell cycle arrest, cytotoxicity and inflammation/atherosclerosis-related modulators production in endothelial cells and mononuclear cells. [PDF]
PLoS ONE, 2014 AIMS: Cresols are present in antiseptics, coal tar, some resins, pesticides, and industrial solvents. Cresol intoxication leads to hepatic injury due to coagulopathy as well as disturbance of hepatic circulation in fatal cases.
Mei-Chi Chang +9 more
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An efficient and highly selective ortho-tert-butylation of p-cresol with methyl tert-butyl ether catalyzed by sulfonated ionic liquids [PDF]
Journal of the Serbian Chemical Society, 2014 A novel series of sulfonic acid-functionalized ionic liquids (SFILs) was found to act as efficient catalysts for ortho-tert-butylation of p-cresol with methyl tert-butyl ether (MTBE) as the tert-butylating agent without an added solvent.
Alamdari Reza Fareghi +2 more
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mSphere, 2022 Renal impairment associated with chronic kidney disease (CKD) causes the buildup of uremic toxins that are deleterious to patient health. Current therapies that manage toxin accumulation in CKD offer an incomplete therapeutic effect against toxins such ...
Gerrit A. Stuivenberg +4 more
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Kinetic Study of the Electrochemical Mineralization of m-Cresol on a Boron-Doped Diamond Anode. [PDF]
, 2012 The kinetics of the electrooxidation of m-cresol in aqueous solution was investigated in a one-compartment flow electrochemical cell with a boron-doped diamond electrode (BDD).
Flox, Cristina +3 more
core +1 more source
Anaerobic oxidation of p-cresol by a denitrifying bacterium [PDF]
Applied and Environmental Microbiology, 1986 Metabolism of p-cresol (pCr) under nitrate-reducing conditions is mediated by the denitrifying bacterial isolate PC-07. The methyl substituent of the substrate is oxidized anaerobically by whole-cell suspensions of PC-07 through a series of dehydrogenation and hydration reactions to yield p-hydroxybenzoate (pOHB) in stoichiometric proportions.
I D, Bossert, L Y, Young
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Serum Concentration of p-Cresol and Indoxyl Sulfate in Elderly Hemodialysis Patients
International Journal of Gerontology, 2011 Background: Uremic syndrome is a consequence of the retention of uremic solutes. Indoxyl sulfate (IS) and para-cresol (p-cresol) belong to the group of protein-bound uremic toxins that are poorly cleared by dialysis and are associated with poor clinical ...
Cheng-Jui Lin +5 more
doaj +1 more source
Microbe-derived uremic solutes enhance thrombosis potential in the host
mBio, 2023 p-Cresol sulfate (pCS) and indoxyl sulfate (IS), gut microbiome-derived metabolites, are traditionally associated with cardiovascular disease (CVD) risks in the setting of impaired kidney function.
Ina Nemet +15 more
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