Results 51 to 60 of about 26,088,543 (284)
Purpose: to determine the impact of fitness classes with the priority use of roller skating on the morphofunctional state and physical fitness of schoolchildren in grades 5–6.
Nataliia Pangelova , Sofiia Vlasova
doaj +1 more source
The increasing extreme weather and climate events have a significant impact on the resistance and resilience of Norway spruce trees. The responses and adaptation of individual trees to certain factors can be assessed through the tree breeding programmes.
Endijs Bāders +6 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Student Peer Assessment on the Amphibious Dissection Practices
The aims of this research to determine the implementation and the responses of students about peer assessment in assessing the performance of amphibious dissection practices.
Dwi Ratnasari +2 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Locating-Chromatic Number of Bipartite Graphs
The locating-chromatic number of a graph combines proper vertex coloring with vertex identification through distances to color classes. Although this parameter has been studied for many graph families, general results for bipartite graphs remain limited.
Dian Kastika Syofyan +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
About finite solvable groups with exactly four $p$-regular conjugacy classes
The finite groups with three \(p\)-regular classes were considered by \textit{Y. Ninomiya} [Arch. Math. 57, No. 2, 105-108 (1991; Zbl 0774.20007), Can. J. Math. 43, No. 3, 559-579 (1991; Zbl 0738.20012) and 45, No. 3, 626 (1993; Zbl 0826.20011)]. Let \(p\) be an odd prime.
openaire +3 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

