Results 51 to 60 of about 143,793 (250)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

On b-edge consecutive edge labeling of some regular tree

open access: yesIndonesian Journal of Combinatorics, 2020
Let G = (V, E) be a finite (non-empty), simple, connected and undirected graph, where V and E are the sets of vertices and edges of G. An edge magic total labeling is a bijection α from V ∪ E to the integers 1, 2, . . .
Kiki Ariyanti Sugeng, Denny R. Silaban
doaj   +1 more source

Finite groups with many p-regular conjugacy classes

open access: yesJournal of Algebra
Let $G$ be a finite group and let $p$ be a prime. In this paper, we study the structure of finite groups with a large number of $p$-regular conjugacy classes or, equivalently, a large number of irreducible $p$-modular representations. We prove sharp lower bounds for this number in terms of $p$ and the $p'$-part of the order of $G$ which ensure that $G$
openaire   +3 more sources

About finite solvable groups with exactly four $p$-regular conjugacy classes

open access: yesHokkaido Mathematical Journal, 1996
The finite groups with three \(p\)-regular classes were considered by \textit{Y. Ninomiya} [Arch. Math. 57, No. 2, 105-108 (1991; Zbl 0774.20007), Can. J. Math. 43, No. 3, 559-579 (1991; Zbl 0738.20012) and 45, No. 3, 626 (1993; Zbl 0826.20011)]. Let \(p\) be an odd prime.
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The effects of acrobatics on morphological characteristics of school children

open access: yesTurkish Journal of Kinesiology, 2018
The aim of this paper is to determine the effects of acrobatic elements on changes in morphological characteristics in children who were experimentally treated.
Dušan Mićović   +3 more
doaj   +1 more source

Reducing Aggression and Improving Physical Fitness in Adolescents Through an After-School Volleyball Program

open access: yesFrontiers in Psychology, 2020
This study aimed to determine the effects of an after-school volleyball program on aggression and physical fitness in 14–16 years old students. One hundred and seven participants were randomized to a small-sided volleyball (SSV) training group or a ...
Nebojša Trajković   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy