Results 61 to 70 of about 143,793 (250)

$H^{s,p}$ regularity theory for a class of nonlocal elliptic equations

, 2019
28 pages.
openaire   +2 more sources

On p-parts of Brauer character degrees and p-regular conjugacy class sizes

, 2018
Let $G$ be a finite group, $p$ a prime, and $IBr_p(G)$ the set of irreducible $p$-Brauer characters of $G$. Let $\bar e_p(G)$ be the largest integer such that $p^{\bar e_p(G)}$ divides $χ(1)$ for some $χ\in IBr_p(G)$. We show that $|G:O_p(G)|_p \leq p^{k \bar e_p(G)}$ for an explicitly given constant $k$. We also study the analogous problem for the $p$-
Bessenrodt, Christine, Yang, Yong
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Assessment of postural stability of 14-year-old girls training volleyball

Baltic Journal of Health and Physical Activity
Introduction: Measurements of postural stability are carried out for the prevention of injuries and for rehabilitation of athletes who have sustained traumatic injuries. The aim of the study was to assess postural stability measured in static and dynamic
Robert WALASZEK, Wiesław CHWAŁA, Katarzyna BURDACKA, Marcin BURDACKI, Paweł KUROWSKI   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Inclusão de alunos com necessidades educativas especiais na escola de ensino regular

Eventos Pedagógicos, 2016
O artigo discorre sobre a inclusão do aluno com necessidades educativas especiais na escola de ensino regular. A pesquisa, de abordagem qualitativa, teve como instrumento de coleta de dados entrevistas semiestruturadas com quatro professores.
Fernanda Aparecida Viana Ledesman
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Fuzzy Soft Topological Approaches Based on p-Fuzzy Soft Ω-Open Sets

Journal of Mathematics
In this study, we introduce new classes of fuzzy soft open sets, namely, p-FSΩ-open (respectively, p-FSΩP-open, p-FSΩS-open, p-FSΩα-open, and p-FSΩγ-open) sets in fuzzy soft topological spaces (FSTSs) based on fuzzy topologies in view of Šostak.
Jawaher Al-Mufarrij, Maha M. Saeed, Islam M. Taha   +2 more
doaj   +1 more source