Results 91 to 100 of about 4,044,006 (282)
Optimized processing method of P-S-N curves for high cycle fatigue of aero-engine materials
Journal of Aeronautical Materials, 2020 High cycle fatigue P-S-N curve of material are important for the design of aero-engine strength. Based on the data processing requirement of the high cycle fatigue of aero-engine materials, a novel data processing method has been developed by proposing the criterion of selecting fitting model and the method for determining the critical stress between ...
XU Wei +5 more
openaire +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Particle Swarm Optimization-Based Unconstrained Polygonal Fitting of 2D Shapes
AlgorithmsIn this paper, we present a general version of polygonal fitting problem called Unconstrained Polygonal Fitting (UPF). Our goal is to represent a given 2D shape S with an N-vertex polygonal curve P with a known number of vertices, so that the ...
Costas Panagiotakis
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2015 Objective To investigate the diagnostic value of expression level of serum cystatin C (Cys-C) on early diagnosis of newly diagnosed Parkinson's disease with mild cognitive impairment (PD-MCI).
Can-can MA +9 more
doaj
Chern-Simons theory on spherical Seifert manifolds, topological strings and integrable systems
, 2015 We consider the Gopakumar-Ooguri-Vafa correspondence, relating ${\rm U}(N)$ Chern-Simons theory at large $N$ to topological strings, in the context of spherical Seifert 3-manifolds. These are quotients $\mathbb{S}^{\Gamma} = \Gamma\backslash\mathbb{S}^3$
Borot, Gaetan, Brini, Andrea
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Cancer MedicineBackground Limited evidence exists on the diagnostic performance of Artificial Intelligence (AI)‐assisted Simplified Prostate Imaging Reporting and Data System version 2.1 (S‐PI‐RADS v2.1) combined with quantitative MRI parameters for detecting ...
Xin Li +5 more
doaj +1 more source
AerospaceThis study focuses on high-cycle fatigue (HCF) of aircraft landing gear (LG) components, covering material testing, full-scale component experiments, finite element (FE) modeling, life-prediction comparison, and probabilistic assessment.
Haihong Tang +5 more
doaj +1 more source