Results 71 to 80 of about 4,044,006 (282)

FATIGUE CHARACTERISTICS OF CERTAIN ENGINE FAN BLADE UNDER HIGH-LOW CYCLE COMBINED LOADING

Jixie qiangdu, 2016
In order to carry on life determination on certain engine fan blade,high and low cycle fatigue tests were conducted on several specimens. The fatigue characteristic curve（ S-N curve,P-S-N curve） was obtained by statistical analysis.The results show that ...
TANG Ling, SHANG BoLin, CHEN PengFei, GAO XingWei, YIN ZhiPeng   +4 more
doaj  

On the Quantum Density of States and Partitioning an Integer

, 2003
This paper exploits the connection between the quantum many-particle density of states and the partitioning of an integer in number theory. For $N$ bosons in a one dimensional harmonic oscillator potential, it is well known that the asymptotic (N ...
Abramowitz, Andrews, Apostol, Ashtekar, Auluck, Bethe, Bhaduri, Bohr, Brack, Chase, Das, Erdos, Frautschi, Grossmann, Hagedorn, Hardy, Holthaus, Jennings, Kapusta, Kubo, M.V.N Murthy, Muoi N Tran, Navez, Rademacher, Rademacher, Rajat K Bhaduri, Rosenzweig, Sakhr, Tran   +28 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Intubation Learning Curve with the HugeMed Video Laryngoscope among Anesthesiology Postgraduate Students: An Observational Study

Bali Journal of Anesthesiology
Background: Video laryngoscopy (VL) facilitates intubation by providing an indirect view of the glottis. To determine VL intubation success, establishing its learning curve is important.
Udita Naithani, Siddharth Khatri, Shweta Jain, Surendra Kumar Sethi, Santosh Choudhary, Chandra Prakash Sharma   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Assessment of diastolic dysfunction: comparison of different cardiovascular magnetic resonance techniques

ESC Heart Failure, 2020
Aims Heart failure with preserved ejection fraction is still a diagnostic and therapeutic challenge, and accurate non‐invasive diagnosis of left ventricular (LV) diastolic dysfunction (DD) remains difficult.
Josephine Kermer, Julius Traber, Wolfgang Utz, Pierre Hennig, Marius Menza, Bernd Jung, Andreas Greiser, Philipp Barckow, Florian vonKnobelsdorff‐Brenkenhoff, Agnieszka Töpper, Edyta Blaszczyk, Jeanette Schulz‐Menger   +11 more
doaj   +1 more source