Results 41 to 50 of about 43,321 (262)

Smoothing migration intensities with P-TOPALS

open access: yesDemographic Research, 2020
Background: Age-specific migration intensities often display irregularities that need to be removed by graduation, but two current methods for doing so, parametric model migration schedules and non-parametric kernel regression, have their limitations ...
Sigurd Dyrting
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Use of nonparametric regression methods for developing a local stem form model

open access: yesJournal of Forest Science, 2014
A local mean stem curve of spruce was represented using regression splines. Abilities of smoothing spline and P-spline to model the mean stem curve were evaluated using data of 85 carefully measured stems of Norway spruce. For both techniques the optimal
K. Kuželka, R. Marušák
doaj   +1 more source

Simultaneous probability statements for Bayesian P-splines [PDF]

open access: yesStatistical Modelling, 2008
P-splines are a popular approach for fitting nonlinear effects of continuous covariates in semiparametric regression models. Recently, a Bayesian version for P-splines has been developed on the basis of Markov chain Monte Carlo simulation techniques for inference.
Andreas Brezger, Stefan Lang
openaire   +4 more sources

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Associations of brominated flame retardants exposure with chronic obstructive pulmonary disease: A US population-based cross-sectional analysis

open access: yesFrontiers in Public Health, 2023
BackgroundsWhether there existed an association between brominated flame retardants (BFRs) and chronic obstructive pulmonary disease (COPD) prevalence in humans is still a mystery.ObjectiveTo investigate the association between serum single or mixture ...
Lu Han, Qi Wang
doaj   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree   +9 more
wiley   +1 more source

Evaluating different methods of microarray data normalization

open access: yesBMC Bioinformatics, 2006
Background With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thousands of genes.
Ferreira Carlos   +4 more
doaj   +1 more source

Semiparametric finite mixture of regression models with Bayesian P-splines

open access: yesAdvances in Data Analysis and Classification, 2022
AbstractMixture models provide a useful tool to account for unobserved heterogeneity and are at the basis of many model-based clustering methods. To gain additional flexibility, some model parameters can be expressed as functions of concomitant covariates.
Berrettini, M   +2 more
openaire   +3 more sources

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