Results 81 to 90 of about 43,843 (275)

High-dimensional Structured Additive Regression Models: Bayesian Regularisation, Smoothing and Predictive Performance [PDF]

open access: yes, 2009
Data structures in modern applications frequently combine the necessity of flexible regression techniques such as nonlinear and spatial effects with high-dimensional covariate vectors. While estimation of the former is typically achieved by supplementing
Fahrmeir, Ludwig   +2 more
core   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

open access: yesAdvanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre   +12 more
wiley   +1 more source

Analyzing Temperature Effects on Mortality Within the R Environment: The Constrained Segmented Distributed Lag Parameterization

open access: yesJournal of Statistical Software, 2010
Here we present and discuss the R package modTempEff including a set of functions aimed at modelling temperature effects on mortality with time series data.
Vito M. R. Muggeo
doaj  

A geoadditive Bayesian latent variable model for Poisson indicators [PDF]

open access: yes, 2006
We introduce a new latent variable model with count variable indicators, where usual linear parametric effects of covariates, nonparametric effects of continuous covariates and spatial effects on the continuous latent variables are modelled through a ...
Fahrmeir, Ludwig, Steinert, Sven
core   +3 more sources

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

open access: yesAdvanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel   +12 more
wiley   +1 more source

Nanoarchitectonics of Porous Carbons Templated by Inorganic Metal Oxides and Alkali Metal Salts for Energy and Environmental Applications

open access: yesAdvanced Science, EarlyView.
This review explores inorganic metal oxides and metal salt nanoparticles templated porous carbons, highlighting their synthesis, structural features, and performance in energy and environmental applications. It critically compares template types, porosity control, and functional outcomes across recent literature.
Gurwinder Singh   +8 more
wiley   +1 more source

SEMIPARAMETRIC MODELS AND P-SPLINES [PDF]

open access: yes
P-splines were introduced by Eilers and Marx (1996). We consider semiparametric models where the smooth part of the model can be described by P-splines. A mixed model representation is also considered.
Currie, I., Durbán, M.
core  

Efficient and automatic methods for flexible regression on spatiotemporal data, with applications to groundwater monitoring [PDF]

open access: yes, 2015
Fitting statistical models to spatiotemporal data requires finding the right balance between imposing smoothness and following the data. In the context of P-splines, we propose a Bayesian framework for choosing the smoothing parameter which allows the ...
Bowman, A.W.   +4 more
core   +2 more sources

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

open access: yesAdvanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman   +3 more
wiley   +1 more source

Predicting Cancer Mortality using ANOVA-type P-spline Models

open access: yesRevstat Statistical Journal, 2015
REVSTAT-Statistical Journal, Vol. 13 No.
María Dolores Ugarte   +2 more
openaire   +2 more sources

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