Results 101 to 110 of about 7,592,442 (289)
Nonlinear initial-value problems with positive global solutions
Electronic Journal of Differential Equations, 2003 We give conditions on $m(t)$, $p(t)$, and $f(t,y,z)$ so that the nonlinear initial-value problem {gather*} frac{1}{m(t)} (p(t)y')' + f(t,y,p(t)y') = 0,quadmbox{for }t>0, y(0)=0,quad lim_{t o 0^+} p(t)y'(t) = B, end{gather*} has at least one positive ...
John V. Baxley, Cynthia G. Enloe
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Electronic Journal of Differential Equations, 2003 In this article, we study the differential equation $$ (-1)^{n-p} x^{(n)}(t)=f(t,x(t),x'(t),dots,x^{(n-1)}(t)), $$ subject to the multi-point boundary conditions $$displaylines{ x^{(i)}(0)=0 quad hbox{for }i=0,1,dots,p-1,cr x^{(i)}(1)=0 quad hbox{for }i ...
Yuji Liu, Weigao Ge
doaj
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Phase transition of zircon at high P-T conditions
Phase transition of zircon at high P-T conditionsIn situ observations of the zircon-reidite transition in ZrSiO4 were carried out using a multianvil high-pressure apparatus and synchrotron radiation. The phase boundary between zircon and reidite was determined to be P (GPa) = 8.5 + 0.0017×(T-1200) (K) for temperatures between 1100-1900 K.
openaire
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source