Results 51 to 60 of about 7,087,225 (342)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Not p-Values, Said a Little Bit Differently

open access: yesEconometrics, 2019
As a contribution toward the ongoing discussion about the use and mis-use of p-values, numerical examples are presented demonstrating that a p-value can, as a practical matter, give you a really different answer than the one that you want.
Richard Startz
doaj   +1 more source

A Proposed Hybrid Effect Size Plus p -Value Criterion: Empirical Evidence Supporting its Use [PDF]

open access: yes, 2019
DOI: 10.1080/00031305.2018.1564697 When the editors of Basic and Applied Social Psychology effectively banned the use of null hypothesis significance testing (NHST) from articles published in their journal, it set off a fire-storm of ...
Goodman, William M.
core  

Circulating leukocyte telomere length is highly heritable among families of Arab descent [PDF]

open access: yes, 2012
Background Telomere length, an indicator of ageing and longevity, has been correlated with several biomarkers of cardiometabolic disease in both Arab children and adults.
AS Al-Rethaiaa   +30 more
core   +3 more sources

Manipulating the Alpha Level Cannot Cure Significance Testing

open access: yesFrontiers in Psychology, 2018
We argue that making accept/reject decisions on scientific hypotheses, including a recent call for changing the canonical alpha level from p = 0.05 to p = 0.005, is deleterious for the finding of new discoveries and the progress of science.
David Trafimow   +67 more
doaj   +1 more source

Critique of p‐Values

open access: yesInternational Statistical Review, 2006
SummaryThis paper generalizes the notion of p‐value to obtain a system for assessing evidence in favor of an hypothesis. It is not quite a quantification in that evidence is a pair of numbers (the p‐value and the p‐value with null and alternative interchanged) with evidence for the alternative being claimed when the first number is small and the second
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

HUBUNGAN FAKTOR KARAKTERISTIK, TINGKAT PENGETAHUAN DAN SIKAP DENGAN PRAKTEK STERILISASI [PDF]

open access: yes, 2003
RSU Kardinah Tegal pusat pelayanan kesehatan, salah satu jenis pelayanan adalah Sterilisasi pada wanita, dari 105 orang pasca melahirkan perbulan hanya 10,48% yang menjalani sterilisasi, rendahnya angka tersebut bila dibandingkan dengan angka peserta KB ...
Wahyudin, Riyanto
core  

Emergency Undocking Curriculum in Robotic Surgery [PDF]

open access: yes, 2019
Introduction Traditional instruction for robotic surgery is typically devoid of training that addresses the delineation of interprofessional roles for operating room personnel.
Ahmed, Rami   +3 more
core   +1 more source

Efficiency of earthquake forecast models based on earth tidal correlation with background seismicity along the Tonga–Kermadec trench

open access: yesEarth, Planets and Space, 2022
The correlation between Earth’s tides and background seismicity has been suggested to become stronger before great earthquakes and weaker after. However, previous studies have only retrospectively analyzed this correlation after individual large ...
Fuyuki Hirose   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy