Results 151 to 160 of about 43,193,860 (312)
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Does Social Capital Have a Role in Environmental Kuznets Curve? Spatial Panel Regression Approach [PDF]
We advance a case for an inclusion of social capital in the environmental Kuznets curve analysis using highly disaggregated data on water pollution in Louisiana.
Zapata, Hector O. +3 more
core
The Marshall-Lerner condition, the J-curve and S-curve have emerged as theoretical and empirical foundations developed for the study of the interaction between exchange rates and international patterns of bilateral trade. They have a significant bearing
Lorena Andrea Palacios-Chacón +1 more
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Understanding the Flattening Phillips Curve [PDF]
Policy-makers have recently noted an apparent flattening of the Phillips curve. The implications of such a change include that a positive output gap would be less inflationary, but the cost of reducing inflation, once established, would increase.
Tim Robinson, Ken Kuttner
core
Numerical Centrifugal Test Study on Large-diameter Steel Pipe Pile under Horizontal Load
:Large-diameter steel pipe pile is a kind of single pile which is widely used in offshore wide farm. Based on the centrifugal model test results of large-diameter steel pipe pile under horizontal load, we conducted the centrifugal numerical test by 3D ...
jiang jiwei
doaj
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
PD-L1 immunoreactivity and its association with tumor grade in canine mammary carcinomas. [PDF]
Duarte-Isaza GP +4 more
europepmc +1 more source

