Results 51 to 60 of about 889,323 (267)

Static and cyclic p-y curves for laterally loaded piles in soft clay

open access: yesYantu gongcheng xuebao, 2017
A pseudo-three-dimensional analysis method on static p-y curves of laterally loaded piles in soft clay is conducted. This method is based on the two-dimensional elastic fictitious loading upper bound limit analysis approach considering the stress-strain ...
HUANG Mao-song 1, 2, MA Hao 1, 2, LI Sen 1, 2, YU Jian 1, 2, ZHANG Chen-rong 1, 2
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation of lateral capacity for flexible drilled shafts in cohesionless soils

open access: yesScience Progress, 2022
This study aimed to evaluate and improve the p – y curve method for use in the lateral analysis of flexible circular drilled shafts in cohesionless soils.
Ssu-An Chou   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Response of Monopiles Under Lateral Loading By Centrifuge Modeling

open access: yesنشریه مهندسی دریا, 2016
One of the most common methods to analyze and design monopiles under lateral load is load-displacement curves, particularly the p-y curves, at different locations of the structure.
Hamid Reza Khodaei   +2 more
doaj  

Study on the Dynamic Response Characteristics and p–y Curve of Straight and Inclined Pile Groups in Saturated Sands

open access: yesApplied Sciences, 2022
This paper is based on a shaking table test of 2 × 2 straight pile groups and 2 × 2 inclined pile groups in non-liquefied sand and saturated sand with different thicknesses.
Yurun Li   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Design of Laterally Loaded Piles in Cohesive Soils Using p-y Curves

open access: yesSoils and Foundations, 1998
ABSTRACT The paper presents the results from a series of tests in Shanghai, PRC on laterally loaded single piles in a medium stiff clay. The diameter of the piles varied from 0.09 m to 0.60 m. The piles were instrumented with strain gauges to determine the moment distribution along the piles and the lateral deflections.
WU, DONGQING   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Deformation Analysis of Large Diameter Monopiles of Offshore Wind Turbines under Scour

open access: yesApplied Sciences, 2020
The displacement of monopile supporting offshore wind turbines needs to be strictly controlled, and the influence of local scour can not be ignored. Using p–y curves to simulate the pile–soil interaction and the finite difference method to calculate ...
Zhaoyao Wang   +5 more
doaj   +1 more source

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