Results 61 to 70 of about 889,323 (267)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

CURVAS DE TRANSFERENCIA DE CARGA HORIZONTAL p-y PARA SUELOS LIMOSOS LOÉSSICOS CURVAS DE TRANSFERÊNCIA DE CARGA HORIZONTAL p-y PARA SOLOS LIMOSOS LOÉSSICOS HORIZOTAL LOAD TRANSFERENCE p-y CURVE FOR SILTY LOESS SOILS

Revista EIA, 2009
Las fundaciones profundas excavadas pueden estar sometidas a solicitaciones horizontales. En esta condición, el análisis de comportamiento resulta complejo debido a la tridimensionalidad del problema.
PEDRO A ARRÚA, GONZALO M AIASSA
doaj  

Investigation of p-y Behaviors of a Cyclic Laterally Loaded Pile in Saturated Silty Sand

Advances in Civil Engineering, 2022
This study aimed to evaluate the p-y behavior of pile foundations installed in saturated silty sand subject to cyclic lateral loading. Model piles were installed in saturated silty sand with three relative densities (40%, 70%, 90%), and lateral loads of ...
Sung-Ha Baek, Joonyoung Kim
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Study on the load-bearing behavior of rock-socketed piles under multidirectional horizontal cyclic loading

河南理工大学学报. 自然科学版
ObjectivesThe horizontal load-bearing mechanism of rock-socketed single piles under different loading paths remains unclear. Therefore， this study investigates the load-bearing behavior of rock-socketed piles subjected to multidirectional horizontal ...
Zheng Can, Shang Wenchang, Song Hexing, Liu Junwei, Lai Huaiyuan, Hu Yukun, Qi Guangyu, Zhang Yingyu, Dai Xingke   +8 more
doaj   +1 more source

Cyclic p-y Curves of Monopiles in Dense Dry Sand Using Centrifuge Model Tests

Applied Sciences, 2019
In this study, centrifuge model tests were used to examine the lateral behavior of a monopile embedded in dry sand through cyclic lateral loading tests.
Myungjae Lee, Kyung-Tae Bae, Il-Wha Lee, Mintaek Yoo   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Dynamic p-y Model for Laterally Loaded Piles near Clay Slope

Applied Sciences
Seismic loading can significantly affect the safety and serviceability of structures supported by piles, making seismic performance a key consideration in pile foundation design.
Chong Jiang, Yunfei Zhang, Ziqian Ding, Fanhuan Zeng   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source