Results 91 to 100 of about 3,388,319 (280)

Lateral load capacity of flexible piles in the SDMC model with cylindrical cavity expansion theory

Scientific Reports
This paper presents a method for calculating the lateral load capacity of flexible piles based on the state-dependent Mohr-Coulomb (SDMC) model combined with cylindrical cavity expansion theory. The soil surrounding the pile is idealized as a cylindrical
Feng Gao, Chengcong Hu, Biao Huang, Li Pang   +3 more
doaj   +1 more source

Lateral Deflection of Single Pile due to Lateral Loads in Clay Soils based on The P-Y Curve Method with Finite Difference Solution, ALLPILE Program, and PLAXIS Program

Jurnal Teknik Sipil dan Perencanaan, 2019
The foundation has a function to hold the load in the form of axial load, lateral load and moment. The axial load on the pile foundation is supported by the pole end resistance and pile friction, while the lateral load on the pile foundation is supported
Ahmad Jirjisul Ba'ist, Togani Cahyadi Upomo, Henry Apriyatno, Untoro Nugroho   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Study on p-y Curves with Pressuremeter Tests in Jeju Basalt Rock

Journal of the Korean Geosynthetic Society, 2015
Recently, offshore wind farms are increasingly expected, because there are huge resource and large site in offshore. Jeju island has optimum condition for constructing a wind energy farm. Unlike the mainland, Jeju island has stratified structure distribution between rock layers sediments due to volcanic activation.
Ki-Ho Yang, Jong-Chul Huh, Jeong-Jun Park   +2 more
openaire   +2 more sources

Wild monodromy and automorphisms of curves

, 2006
Let $R$ be a complete discrete valuation ring of mixed characteristic $(0,p)$ with field of fractions $K$ containing the $p$-th roots of unity. This paper is concerned with semi-stable models of $p$-cyclic covers of the projective line $C \la \PK$.
Lehr, Claus, Matignon, Michel
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Calculation model for lateral response of piles considering the characteristics of sand convection under asymmetric cyclic loading

Applied Ocean Research
Pile foundations supporting wind turbines and offshore platforms are always subjected to asymmetric lateral cyclic loads from wind and waves. To calculate the lateral response of the pile in sand under asymmetric cyclic loading, this paper proposes a p−y
Fanhuan Zeng, Chong Jiang
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

P-y curve models for laterally loaded lattice-shaped diaphragm wall as sea-crossing bridge foundations

Applied Ocean Research
Lattice-shaped diaphragm walls (LSDWs) are novel foundation systems increasingly used in large-span, deep-water bridges for their exceptional rigidity, cost-efficiency, and adaptability to diverse geotechnical and marine environments.
Jiujiang Wu, Longjun Pu
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source