Results 111 to 120 of about 43,193,860 (312)

P-y curve models for laterally loaded lattice-shaped diaphragm wall as sea-crossing bridge foundations

open access: yesApplied Ocean Research
Lattice-shaped diaphragm walls (LSDWs) are novel foundation systems increasingly used in large-span, deep-water bridges for their exceptional rigidity, cost-efficiency, and adaptability to diverse geotechnical and marine environments.
Jiujiang Wu, Longjun Pu
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Wage Curve Reloaded [PDF]

open access: yes
This paper provides evidence for the existence of a wage curve -- a micro-econometric association between the level of pay and the local unemployment rate -- in modern U.S. data. Consistent with recent evidence from more than 40 other countries, the wage
David G. Blanchflower, Andrew J. Oswald
core  

monicarenas4/hyperelliptic-curve-pairings: Hyperelliptic curve pairings

open access: yes
<p>Elliptic Curve Cryptography and Hyperelliptic Curves (genus 2)</p ...
Georgios Fotiadis   +2 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Economic growth and environmental quality: a meta-analysis of environmental Kuznets curve studies [PDF]

open access: yes
Meta-analysis is used to investigate systematic variation across Environmental Kuznets Curve (EKC) studies. Based on 588 observations, modeling results indicate that data characteristics, study methods, estimation techniques, and the chosen environmental
Therese Grijalva   +2 more
core  

The Derivation and Application of a Theoretically and Economically Consistent Version of the Nelson and Siegel Class of Yield Curve Models [PDF]

open access: yes, 2007
A popular class of yield curve models is based on the Nelson and Siegel (1987) (hereafter NS) approach of fitting yield curve data with simple functions of maturity.
Krippner, Leo
core  

A Review of Static and Dynamic p-y Curve Models for Pile Foundations

open access: yesBuildings
In addition to supporting vertical loads from superstructures, piles are frequently subjected to horizontal soil pressures, long-term wind, wave, and current forces, as well as seismic loads.
Jiujiang Wu, Longjun Pu, Changming Zhai
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Combating curve squeal noise

open access: yes, 2016
Society demand for more sustainable transports is increasing, starting a modal shift from road to railway. The resulting increase in railway traffic intensity is leading to more activities on the track, even during the night time.
Rantatalo, Matti,   +3 more
core  

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