Results 81 to 90 of about 3,388,319 (280)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Proyek pembangunan Kota Baru-Summarecon Bandung terletak pada kawasan Gedebage Bandung Timur. Kawasan ini merupakan area bekas sawah sehingga memiliki jenis tanah yang sangat lunak (dominan lempung) dengan NSPT rata-rata sebesar 2.
Ali Kurniawan Ngunaidi +2 more
doaj
Polarization types of isogenous Prym-Tyurin varieties
Let p:C-->Y be a covering of smooth, projective curves which is a composition of \pi:C-->C' of degree 2 and g:C'-->Y of degree n. Let f:X-->Y be the covering of degree 2^n, where the curve X parametrizes the liftings in C^{(n)} of the fibers of g:C'-->Y.
Kanev, Vassil, Lange, Herbert
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Accuracy evaluation of API P-Y model for Offshore Piles in Clays
Piles are widely used as foundation structures supporting offshore wind turbines, with the p-y curve method commonly recommended for analysis of pile-soil interactions by current mainstream design specifications.
Peiyuan Lin +4 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
While methods like cyclic triaxial testing and p-y model updating theory exist in geotechnical and offshore wind engineering, they have not been systematically applied to solve the specific deformation problems of offshore PV piles.
Sai Fu +4 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

