Results 101 to 110 of about 586,855 (294)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

open access: yesAdvanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet   +8 more
wiley   +1 more source

A Generalization of the Havrda-Charvat and Tsallis Entropy and Its Axiomatic Characterization

open access: yesAbstract and Applied Analysis, 2014
In this communication, we characterize a measure of information of types α, β, and γ by taking certain axioms parallel to those considered earlier by Havrda and Charvat along with the recursive relation Hn(p1,…,pn; α, β, γ) - Hn-1(p1+p2, p3,…,pn; α, β, γ)
Satish Kumar, Gurdas Ram
doaj   +1 more source

P1 or P1[over-bar]? Or something else? [PDF]

open access: yes, 1999
The October 1998 release of the Cambridge Structural Database (1992) contains structural details (unit-cell dimensions and atom coordinates) for nearly 1300 distinct entries under space group P1 (No.
Marsh, Richard E.
core  

P1-puhtausluokan toimintaohjeet [PDF]

open access: yes, 2020
Opinnäytetyön tavoitteena oli tuottaa helppolukuiset ja tiivistetyt ohjeet P1-puhtausluokan vaatimuksista Keski-Hämeen Rakennus Oy:lle. Tilaaja toi ilmi toiveen, että ohjeita pystyisi soveltamaan myös oman tuotannon kohteisiin, joihin ei puhtausluokkaa ...
Rantanen, Emilia
core  

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

P1-puhtausluokka saneerauskohteessa [PDF]

open access: yes, 2018
Tämän opinnäytetyön tarkoituksena oli perehtyä P1-puhtausluokkaan sekä laatia siitä tilaajalle pienimuotoinen P1-käsikirja. Käsikirjan tarkoitus on helpoittaa työmaamestarin työtä P1-puhtausluokan osalta.
Patronen, Karri
core  

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

Sustainable Cold-Chain Logistics for Vaccine and Blood Supply in East Malaysia

open access: yesEngineering Proceedings
Ensuring product integrity across Malaysia’s East Malaysian states (Sabah and Sarawak) requires a cold chain that is resilient to tropical heat, long multimodal routes, intermittent power, and dispersed rural populations.
Yuan Zhi Leong, Wai Yie Leong
doaj   +1 more source

On the Betti numbers of three fat points in P1 × P1

open access: yes, 2019
In these notes we introduce a numerical function which allows us to describe explicitly (and nonrecursively) the Betti numbers, and hence, the Hilbert function of a set Z of three fat points whose support is an almost complete intersection (ACI) in P1 × P1 . A nonrecursively formula for the Betti numbers and the Hilbert function of these configurations
FAVACCHIO, GIUSEPPE, GUARDO, ELENA MARIA
openaire   +3 more sources

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