Results 31 to 40 of about 586,855 (294)

Tình hình dạy và học Anh văn chuyên ngành Môi trường: Ý kiến phản hồi của sinh viên Trường Đại học Tài nguyên và Môi trường thành phố Hồ Chí Minh

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2016
Giỏi tiếng Anh là một trong những điều kiện tiên quyết để giúp chúng ta hội nhập với thế giới. Tiếng Anh giao tiếp là một trong những kỹ năng cơ bản để thiết lập các mối quan hệ và tương tác giữa con người với nhau trong công cuộc hội nhập; trong khi đó ...
Lý Cẩm Hùng, Nguyễn Thị Lê Phi
doaj   +1 more source

Transcriptional analysis of cultures upon hydrogen peroxide treatment using the novel standard A-P1-1

open access: yes, 2011
D B-P1 indicate the five promoter of operons in [48]. (b) Validation of the A-P1 promoter as qRT-PCR reference product; by definition, the value of the control is one (see Methods), the statistical significance of data was determined by applying one-way ...
María J García (93964)   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fosas comunes de mujeres: narrativas de la(s) violencia(s) y lugares de dignificación

open access: yesKamchatka: Revista de Análisis Cultural, 2019
A partir del estudio de caso de la exhumación, reinhumación y demarcación territorial como lugar de memoria de dos fosas de mujeres represaliadas en la retaguardia sublevada y franquista en Candeleda (Ávila) y Grazalema (Cádiz), el presente artículo da ...
María Laura Martín Chiappe
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Systemic 5-FU treatment caused delayed increases in auditory brainstem response (ABR) inter-peak latencies P2-P1 and P3-P1

open access: yes, 2011
Baseline ABR hearing tests were performed on each animal one day before initiation of treatment with 5-FU (as for Figure 4). After treatment ended, follow-up ABR tests were conducted on each animal at various points during a time course of 56 days ...
Margot Mayer-Proschel (21190)   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Sediment characteristics of core LYL-P1-14 from Ymer Lake, East Greenland

open access: yes, 2018
We fingerprint the geomorphological expression of Holocene climate transitions from East Greenland lake sediments (core LYL-P1-14) using physical (grain size, oragnic content - LOI, sediment density - DBD), visual (3-D Computed Tomography) and ...
Matteo Spagnolo (8022536)   +11 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy